Cardioskeletal Myopathies in Children and Young Adults

Dr. Jefferies is a recognized international expert in the field of heart muscle disease contributing much of the current literature regarding related genetic mechanisms, clinical investigation, and guideline development. Dr. Blaxall is a renowned translational basic scientist who has significantly contributed the current understanding of myocardial signalling pathways and myocyte hypertrophy. Dr. Chin is a senior investigator in the field of pediatric cardiac transplantation who is actively involved with development of novel methods for diagnosing and treating humeral and cellular rejection. Dr. Towbin is a recognized international expert in the field of heart muscle disease contributing much of the current literature regarding related genetic mechanisms, clinical investigation, and guideline development. Dr. Robbins is a revered expert in the basic science of cardiomyopathic disease, pioneering animal modelling of genetically based heart muscle disease.

• Section I. Physiology and Molecular Basis of MuscleChapter 1. Ventricular Systolic FunctionChapter 2. Basics of Skeletal Muscle Function and Normal PhysiologyChapter 3. Molecular Pathways in CardiomyopathiesChapter 4. Abnormal Muscle Pathology and PhysiologySection II. Diseases of Cardio-Skeletal PhenotypesChapter 5. Dilated Cardiomyopathy and Cardioskeletal InvolvementChapter 6. Hypertrophic CardiomyopathyChapter 7. Restrictive Cardiomyopathy Associated With Skeletal MyopathiesChapter 8. Left Ventricular Noncompaction CardiomyopathyChapter 9. Diseases of the Cytoskeleton: The DesminopathiesChapter 10. Diseases of Cardiac SarcomeresChapter 11. Diseases of the Intercalated DiscChapter 12. Diseases of the Nuclear MembraneSection III. Metabolic Causes of DiseaseChapter 13. Mitochondrial Disorders Causing Cardioskeletal Myopathies in ChildhoodChapter 14. Nonmitochondrial Metabolic Cardioskeletal MyopathiesSection IV. Syndromal and Chromosomal Causes of DiseaseChapter 15. Cardio-Skeletal Muscle Disease Associated With SyndromesChapter 16. Cardioskeletal Muscle Disease Associated With Chromosomal DisordersSection V. Cardio-Skeletal Myopathies Associated With Congenital Heart DiseaseChapter 17. Cardioskeletal Myopathies in Congenital Heart DiseasesSection VI. Future Directions in the Diagnosis and Management of Cardioskeletal Myopathic Disease in Children and Young AdultsChapter 18. Future Diagnostic Strategies—PediatricChapter 19. Neuromodulation of the Failing Heart

"This comprehensive review includes numerous diagrams and illustrations of the molecular disruption, pathology, and various diagnostic modalities in these myopathies. This is an essential tool for researchers and clinicians involved in their research, diagnosis, and treatment. Score: 89 - 3 Stars" --Doody's