Cardiac Repolarization

Bridging Basic and Clinical Science

Häftad, Engelska, 2010

AvIhor Gussak,Charles Antzelevitch,Stephen C. Hammill,Win K. Shen,Preben Bjerregaard

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A comprehensive review of all the latest developments in cardiac electrophysiology, focusing on both the clinical and experimental aspects of ventricular repolarization, including newly discovered clinical repolarization syndromes, electrocardiographic phenomena, and their correlation with the most recent advances in basic science. The authors illuminate the basic electrophysiologic, molecular, and pharmacologic mechanisms underlying ventricular repolarization, relate them to specific disease conditions, and examine the future of antiarrhythmic drug development based on both molecular and electrophysiological properties. They also fully review the clinical presentation and management of specific cardiac repolarization conditions.

Produktinformation

Utgivningsdatum2010-11-09
Mått178 x 254 x 31 mm
Vikt1 054 g
FormatHäftad
SpråkEngelska
SerieContemporary Cardiology
Antal sidor548
FörlagHumana Press Inc.
ISBN9781617373367

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Part I. Introduction Chapter 1. Ventricular Repolarization and the Identification of the Sudden Death Candidate: Hype or Hope?Hein J. Wellens and Douglas P. Zipes Chapter 2. Historical Milestones of Electrical Signal Recording and AnalysisThorsten Lewalter and Berndt Luderitz Part II. Basic Electrophysiology, Pharmacology, and Molecular Biology of Ventricular RepolarizationEdited by Charles Antzelevitch Chapter 3. Physiology and Molecular Biology of Ion Channels Contributing to Ventricular RepolarizationJeanne M. Nerbonne and Robert S. Kass Chapter 4. Electrophysiology and Pharmacology of Ventricular RepolarizationCharles Antzelevitch, Andrew C. Zygmunt, and Robert Dumaine Chapter 5. How Do We Measure Repolarization inside the Heart?Charles Antzelevitch, Andrew C. Zygmunt, Jeffrey Fish, Guillermo Perez, and Fabiana Scornik Chapter 6. Contribution of Electrical Heterogeneity of Repolarization to the ECGCharles Antzelevitch and Vladislav V. Nesterenko Chapter 7. Electrical and Structural Remodeling of the Ventricular Myocardium in DiseaseAntonis A. Armoundas and Gordon F. Tomaselli Chapter 8. Ischemia-Related Changes in RepolarizationAndré G. Kléber and Michiel J. Janse Chapter 9. The Long QT Syndrome: Molecular and Genetic AspectsCarlo Napolitano and Silvia G. Priori Chapter 10. Ion Channel Disease as a Cause of the Brugada Syndrome: Molecular and Genetic AspectsConnie R. Bezzina and Arthur A. M. Wilde Chapter 11. Cellular and Ionic Mechanisms Underlying ArrhythmogenesisCharles Antzelevitch, Alexander Burashnikov, and Jose Di Diego Part III. Clinical Physiology and Pathophysiology of Ventricular Repolarization: Theory and PracticeEdited by Steven C. Hammill, Win K-Kuang Shen, and Ihor Gussak Chapter12. Evaluation of VentricularRepolarization: The Clinician's PerspectiveJan Nemec, Steven C. Hammill, and Win-Kuang Shen Chapter 13. Human Cardiac RepolarizationPhilip T. Sager Chapter 14. QT interval and Its Drug-Induced ProlongationWojciech Zareba and Arthur J. Moss Chapter 15. Neuro-Mediated Repolarization AbnormalitiesPhilippe Coumel and Pierre Maison-Blanche Chapter 16. The Electrophysiologic Matrix: Equilibrium and Arnsdorf's ParadoxMorton F. Arnsdorf Chapter 17. Antiarrhythmic Drugs and Future DirectionArshad Jahangir, Andre Terzic, and Win-Kuan Shen Part IV. Specific Electrocardiographic Phenomena and Clinical Syndromes of Ventricular RepolarizationEdited by Ihor Gussak, Charles Antzelevitch, and Preben Bjerregaard Chapter 18. ECG Phenomena of the Early Ventricular Repolarization: Early Repolarization SyndromeIhor Gussak, Charles Antzelevitch, and Preben Bjerregaard Chapter 19. The Brugada SyndromePedro Brugada, Ramon Brugada, Charles Antzelevitch, Koonlawee Nademanee, Jeffrey Towbin, and Josep Brugada Chapter 20. Clinical Evaluation, Risk Stratification, and Management of Congenital Long QT SyndromeAnant Khositseth and Michael J. Ackerman Chapter 21. Prolonged Repolarization and Sudden Infant Death SyndromePeter J. Schwartz Chapter 22. Short QT Interval: ECG Phenomenon and Clinical Syndrome, Ihor Gussak, Charles AntzelevitchDaniel Goodman, and Preben Bjerregaard Chapter 23. T-Wave Alterans: Mechanisms, Relevance, and Clinical ImplicationsEtienne Pruvot and David S. Rosenbaum. Index.