Cancer and Inflammation

The Novartis Foundation is an international scientific and educational charity which promotes the study and general knowledge of science and in particular encourages international co-operation in scientific research. Chair: SIAMON GORDON, Sir William Dunn School of Pathology, University of Oxford, UK

• Chair's Introduction (S. Gordon). Inflammation and cancer: an epidemiological perspective (M. Thun, et al.).Chemokine-based pathogenetic mechanisms in cancer (I. Conti, et al.).General Discussion I.Anti-TNF therapy of rheumatoid arthritis: what can we learn about chronic disease? (M. Feldmann, et al.).How do chemokine/chemokine receptor activations affect tumorigenesis? (A. Richmond, et al.).Proinflammatory cytokines, immune response and tumour progression (M. Spadaro and G. Forni).General discussion II.Lymphangiogenesis and tumour metastasis (J. Tille, et al.).Infiltration of tumours by macrophages and dendritic cells: tumour-associated macrophages as a paradigm for polarized M2 mononuclear phagocytes (A. Mantovani, et al.).The influence of CD25+ cells on the generation of immunity to tumour cell-lines in mice (E. Jones, et al.).Macrophages: modulators of breast cancer progression (E. Lin and J. Pollard).Chemokines: angiogenesis and metastases in lung cancer (R. Strieter, et al.).Macrophage infiltration and angiogenesis in human malignancy (H. Knowles, et al.).The role of  inflammation for tumour growth and tumour suppression (T. Blankenstein).Cyclooxygenase 2: from inflammation to carcinogenesis (A. Ristimäki).The inflammatory cytokine network of epithelial cancer: therapeutic implications (P. Szlosarek and F. Balkwill).In vivo manipulation of DC migration and activation to elicit anti-tumour immunity (A. Vicari, et al.).Final general discussion.Concluding remarks (S. Gordon).Index of contributors.Subject Index.

"This book…is highly informative, very up-to-date, and demonstrates the complex biochemical events that may result in carcinogenesis." (Doody's Electronic Journal) “…a useful guide to the considered thoughts of those within their field.” (The Newsletter of the British Society of Cell Biology, Summer 2005)