Calculated Risks

The Toxicity and Human Health Risks of Chemicals in our Environment

Inbunden, Engelska, 2027

AvJoseph V. Rodricks,Harvey J. Clewell III

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Chemical products are ubiquitous in the modern world. They offer many economic and societal benefits but can also present threats to human health and can cause pollution related to their manufacture and use. This revised third edition has been significantly updated to include the latest scientific tools and regulations. It begins by describing the principles and practices of epidemiology and toxicology, then proceeds to explain how this research is applied in practice to establish regulations needed to protect health and to develop risk assessment framework. It features an entirely new chapter on emerging risk assessment science, an expanded discussion of exposure science, and the most recent developments in law and regulation., Written in accessible language, Calculated Risks will be of interest to advanced undergraduate and graduate students taking courses in risk assessment, toxicology or environmental chemistry, and to researchers, professionals and decision makers involved in chemical safety and regulation.

Produktinformation

Utgivningsdatum2027-02-28
FormatInbunden
SpråkEngelska
Antal sidor404
Upplaga3
FörlagCambridge University Press
ISBN9781009570695

Tillhör följande kategorier

Miljöekonomi inom Ekonomi och Ledarskap
Miljörätt inom Juridik
Epidemiologi och medicinsk statistik inom Medicin
Miljövetenskap och miljöpolitik inom Naturvetenskap och teknik

Joseph V. Rodricks was a founding principal of ENVIRON International, a consultancy firm focussed on public health and regulatory issues involving substances in the environment. He served as principal scientist at ENVIRON for 35 years, before moving to Ramboll, a Danish consulting firm, until his retirement in 2024. Prior to his work at ENVIRON, he served for 15 years as a scientist at the USFDA, including 5 years as Associate FDA Commissioner for Health Affairs. He has more than 150 scientific publications and has received honorary awards from four professional societies for his contributions to toxicology and risk analysis, and he has served on close to 40 expert committees of the National Academy of Sciences. Harvey J. Clewell has more than 50 years of experience in environmental exposure assessment, toxicology research, chemical risk assessment and hazardous materials management. He gained an international reputation for his pioneering work on the incorporation of mechanistic information and dose-response modeling into chemical risk assessments, having played a key role in the first applications of these approaches by regulatory agencies. He has served on many peer review panels for regulatory agencies in both the US and the EU. He is a recipient of the Society of Toxicology's Arnold J. Lehman Award for major contributions to chemical safety and risk assessment.

Preface to the ﬁrst edition; Preface to the second edition; Preface to the third edition; Science: a footnote; List of abbreviations; Prologue; 1. Chemicals and chemical exposures; 2. From exposure to dose; 3. From dose to toxic response; 4. Identifying toxic substances; 5. Toxic agents and their targets; 6. Carcinogens; 7. Investigating toxicity from human exposures: the science of epidemiology; 8. Risk assessment I: some concepts and principles; 9. Risk assessment II: applications; 10. Risk assessment III: expanding research, rising challenges; 11. Risk assessment IV: the courtroom; 12. The management of risk; 13. Emerging risk assessment science; 14. A look ahead; Sources and recommended reading; Index.