Calcium Signaling In Airway Smooth Muscle Cells

Dr. Yong-Xiao Wang is a Full Professor in the Center for Cardiovascular Sciences at Albany Medical College, USA. He earned his M.D. at the Wannan Medical College and Ph.D. at the Fourth Military Medical University, and received his postdoctoral training at the Technology University of Munich and University of Pennsylvania. Subsequently, Dr. Wang worked as an Assistant Professor in the Department of Animal Biology at the University of Pennsylvania. Dr. Wang has been a first author, key contributor and corresponding author in numerous publications in such high-impact journals such as Circ Res, Proc Natl Acad Sci U S A, Nature, and Antioxid Redox Signal. He has been a principal investigator on several NIH grants. Dr. Wang has collaborated with numerous well-known scientists, received multiple prestigious awards, served in various NIH study sections and other grant review panels, reviewed manuscripts for many scientific journals, and trained a number of scholars (some of whom are independent investigators in the field).

• Ryanodine and Inositol Trisphosphate Receptors/Ca2+ Release Channels in Airway Smooth Muscle Cells.- Kv7 (KCNQ) Potassium Channels and L-type Calcium Channels in the Regulation of Airway Diameter.- Transient Receptor Potential and Orai Channels in Airway Smooth Muscle Cells.- Large-conductance calcium-activated potassium channels.- Calcium-activated Chloride Channels.- Local Calcium Signaling in Airway Smooth Muscle Cells.- Regulation of Airway Smooth Muscle Contraction by Ca2+ Signaling: Physiology Revealed by Microscopy Studies of Lung Slices.- Temporal Aspects of Ca2+ Signaling in Airway Myocytes.- Mechanisms Underlying Ca2+ Store Refilling in Airway Smooth Muscle.- Novel Mechanisms in Ca2+-homeostasis and Internal Store Refilling of Airway Smooth Muscle.- The Role of Mitochondria in Calcium Regulation in Airway Smooth Muscle.- Role of Caveolae in the Airway.- CD38 – Cyclic ADP-ribose-mediated Calcium Signaling in Airway Myocytes.- The Pathways and Signaling Cross-talk with Oxidant in Calcium Influx in Airway Smooth Muscle Cells.- Role of RhoA/Rho-kinase and Calcium Sensitivity in Airway Smooth Muscle Functions.- Role of Integrins in the Regulation of Calcium Signaling.- Sex Steroid Signaling in the Airway.- Regulation of Contractility in Immature Airway Smooth Muscle.- Mathematical Modeling of Calcium Dynamics in Airway Smooth Muscle Cells.- Effects of Inflammatory Cytokines on Ca2+ Homeostasis in Airway Smooth Muscle Cells.- Ca2+ Signaling and P2 Receptors in Airway Smooth Muscle.- Calcium Signaling in Airway Smooth Muscle Remodeling.- Regulation of Intracellular Calcium by Bitter Taste Receptors on Airway Smooth Muscle.- Modulation of Airway Smooth Muscle Contractile Function by TNFa and IL-13 and Airway Hyper-responsiveness in Asthma.- Airway Smooth Muscle Malfunction in COPD.