Cadmium Toxicity

• Overview. Overview of historical and current problems of cadmium pollution in Japan.- Health effects of cadmium in human populations and its relation to cadmium exposure levels. History and present status of Itai-Itai disease.- Pathophysiology of renal and bone lesions in Itai-itai disease.- A long-term follow-up study of the residents exposed to cadmium in Kakehashi River basin.- Effects of cadmium exposure on life prognosis.- Evaluation of cadmium exposure and health effects among rice farmers in Akita prefecture.- Cadmium intake from foods among general population in Japan and Asia.- Rice contamination by cadmium and its remediation. Regulation of cadmium contents in rice.- Molecular mechanism of cadmium accumulation in rice.- Mitigation technologies of cadmium and arsenic in rice.- Development of low-cadmium-accumulating rice.- New aspects in the mechanisms of cadmium toxicity. Novel mechanisms of cadmium-induced cell death.- Cadmium transport and toxicity in the kidney.- Disturbance in phosphorus metabolism by cadmium exposure.

“This well‐written book provides a brief overview of aspects of cadmium toxicity, with a special emphasis on cadmium toxicity and its associated pathology in Japan. It will be useful to readers interested in understanding cadmium toxicity, particularly those who live in and around Japan.” (Partha Kasturi,Doody's Book Reviews, June 21 2019)