Del 0 - Contemporary Cancer Research

Brain Tumors

Inbunden, Engelska, 2004

2 849 kr

Beställningsvara. Skickas inom 10-15 vardagar. Fri frakt för medlemmar vid köp för minst 249 kr.

A comprehensive guide for both scientists and clinicians to recent advances in our understanding of the cellular and molecular processes involved in the initiation, progression, and clinical and biological behavior of brain tumors. The authors review the latest findings on the molecular biology, genetics, epidemiology, and pathology of brain tumors, detailing new knowledge about molecular profiling, molecular pathology and classification, in vitro and in vivo brain tumor models, brain metastasis, and progenitor cell biology. They also discuss in depth the cellular and genetic pathways involved in brain oncogenesis, malignant progression, and therapeutic response, highlighting oncogenes and tumor suppressor genes, DNA damage and repair, invasion and migration, cell cycle, growth factors, signaling, apoptosis, and developmental biology. The discussion of brain tumor therapy focuses on advances in pharmacological thinking, therapeutic modalities, novel therapeutic targets, rational drug design, gene and viral therapies, drug delivery and the blood brain barrier, immunotherapy, and brain imaging.

Produktinformation

Utgivningsdatum2004-11-15
Mått178 x 254 x 25 mm
Vikt1 034 g
FormatInbunden
SpråkEngelska
SerieContemporary Cancer Research
Antal sidor393
Upplaga2005
FörlagHumana Press Inc.
ISBN9781588290427

Tillhör följande kategorier

Onkologi inom Medicin

Epidemiology, Biology, Genetics, and Pathology.- Epidemiology of Brain Tumors.- Molecular Genetics of Tumors of the Central Nervous System.- Molecular Pathology of Nervous System Tumors.- Genetic Modeling of Glioma Formation in Mice.- Biology of Brain Metastasis.- Analysis of Neural Precursor Cells in the Context of Origin of Brain Tumors, Their Treatment, and Repair of Treatment-Associated Damage.- Biology of Primitive Neuroectodermal Tumors.- Mechanisms and Pathways.- Molecular and Cellular Biology of the Blood-Brain Barrier and Its Characteristics in Brain Tumors.- Immune Regulation in the Brain.- Genetic Pathways in the Evolution of Gliomas.- DNA Damage and Repair in the Therapeutic Response of Tumors of the Central Nervous System.- Role of Urokinase-Type Plasminogen Activator Receptor in Human Glioma Invasion.- Regulation of Cell-Cycle and Apoptosis in Human Brain Tumors.- Therapeutics.- Systemic Chemotherapy for Metastatic Tumors of the Central Nervous System.- Radiation Biology and Therapy of Tumors of the Central Nervous System.- Advances in the Management of Cerebral Metastases.- Immunotherapy of Central Nervous System Tumors.- Targeting Drugs to Tumors of the Central Nervous System.- Rational Design and Development of Targeted Brain Tumor Therapeutics.

"This is an important book for the shelves of neuroscience, neurology, neurosurgery, and oncology departments. It's well worth the price." - Doody's Health Sciences Book Review Journal "This book contains a welcome compilation of the known genetic reference with a good description of each abnormality." - The New England Journal of Medicine "...this book is simply indispensable and should be a significant component for all individuals associated with either biology or treatment of gliomas...a thoroughly comprehensive, up-to-date, and timely review... ." - J. Neurosurg