Yasuo Yoshioka,Radiation Oncology Department,The Cancer Institute Hospital of JFCRJun Itami,Department of Radiation Oncology,National Cancer Center HospitalMasahiko Oguchi,Radiation Oncology Department,The Cancer Institute Hospital of JFCRTakashi Nakano,Department of Radiation Oncology,Gunma University

• Part I. General.- 1. History of Japanese brachytherapy.- 2. Japanese brachytherapy in the world.- 3. Deformable image registration in brachytherapy: Beyond dose volume histogram.- Part II. Gynecology.- 4. Moving on from LDR to HDR.- 5. Intracavitary brachytherapy from 2D to 3D.- 6. Midline block (Central shield) .- 7. Hybrid brachytherapy.- 8. Interstitial brachytherapy: radical and salvage.- 9. Asian cooperation and global trend. - Part III. Prostate.- 10. Prostate brachytherapy: the fact and the way to go.-11. How we led Japanese low-dose-rate brachytherapy to successful practice (Urologist perspecitive).- 12. How we led Japanese low-dose-rate brachytherapy to successful practice (Radiation oncologist perspecitive).- 13. HDR monotherapy.- 14. Single-fraction boost HDR.- Part IV. Breast.- 15. Japanese experience and American trend.- 16. Hungarian experience and European trend.- Part V. Head and Neck.- 17. Low-dose-rate brachytherapy for oral cancer.- 18. High-dose-rate brachytherapy for oral cancer.- 19. Eye plaque brachytherapy for retinoblastoma and melanoma.- Part VI. Intraluminal.- 20. Intraluminal brachytherapy for endobronchial cancer.- 21. Intraluminal brachytherapy for esophageal cancer.- 22. Intraluminal brachytherapy for biliary tract cancer.

“It is an informative, easy to follow and very well-written text. … It would be a very interesting read for radiation oncologists and radiotherapy physicists interested in brachytherapy.” (Wojciech Polak, RAD Magazine, September, 2019)