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There is currently no single book with up to date information on osteoclast function and bone resorption. A useful collection of information, not readily available in a concentrated and convenient form on the market. Provides a comprehensive overview of the field.
Osteoclast: Origin and Differentiation.- Osteolytic Enzymes of Osteoclasts.- Regulation of Osteoclast Activity.- Structural Aspects of Bone Resorption.- Inflammatory Cytokines.- Genetics and Mutations Affecting Osteoclast Development and Function.- Clinical Disorders Associated with Alterations in Bone Resorption.- Pharmaceuticals for Bone Disease Targeting the Osteoclast.- Skeletal Complications of Malignancy: Central Role for the Osteoclast.
From the reviews: "Volume 2 in the series Bone Biology and written by US experts, it reviews in 9 chapters the biology, physiology and physiopathology of the osteoclast. It also describes the new drugs which inhibit bone resorption. A very complete, well referenced text, of interest to all who research or treat bone diseases, including pediatric endocrinologists." (Zvi Laron, Pediatric Endocrinology Reviews, Vol. 3 (2), 2005)