Bone Metastases

• Fundamental Concepts of Bone Metastases.- Bone Anatomy, Physiology and Function.- Pathophysiology of Bone Metastases.- Angiogenesis and Bone Metastasis: Implications for Diagnosis, Prevention and Treatment.- Natural History, Prognosis, Clinical Features and Complications of Metastatic Bone Disease.- Bone Biomarkers in Research and Clinical Practice.- Imaging Modalities.- Radiologic Evaluation Of Skeletal Metastases: Role Of Plain Radiographs And Computed Tomography.- The Contribution Of Nuclear Medicine In The Diagnosis Of Bone Metastases.- Magnetic Resonance Imaging Of Metastatic Bone Disease.- Therapeutic Strategies.- Radiotherapy And Bone Metastases.- Biphosphonates In The Management Of Metastatic Bone Disease.- Combined Radiotherapy and Bisphosphonates: State of Art.- Biphosphonates in the Treatment of Bone Metastases – Osteonecrosis of the Jaw.- Surgical Management of Bone Metastases.- The Role of Chemotherapy in the Treatment of Bone Metastases.- Hormonotherapy of Bone Metastases.- Radionuclide Therapy.- Assessment of Therapeutic Response.- Assessment of Therapeutic Response.- Outcome Measures in Bone Metastases Clinical Trials.

From the reviews: "The aim of the book is to provide both an introduction and reference book on the field of metastatic bone disease. ... Each chapter is extensively referenced. The book is very clear and comprehensive. ... the book achieves its twin aims and is an extremely good reference book for those people researching and managing skeletal metastases. It will appeal to researchers, orthopaedic surgeons, oncologists and students ... ." (Robert U. Ashford, European Journal of Orthopaedic Surgery & Traumatology, Vol. 21, 2011)