Biotics and the Gut–Brain Axis in Neurological Disorders

Neeraj Mishra has been serving as Professor and Head of the Department at the Amity Institute of Pharmacy, Amity University, Gwalior, India, since July 2019. With approximately 20 years of experience in teaching and research, Dr. Mishra has made significant contributions to the field. He has over 125 publications in both international and national journals, focusing on novel drug delivery systems, oral delivery of synbiotics, localized drug delivery, and targeted and controlled delivery of nanocarriers and microparticles for treating breast and colon cancer, as well as neurodegenerative disorders. He has authored more than 15 books and 25 book chapters and holds three international patents and three Indian patents. His achievements have been recognized with several awards, including the “Distinguished Professor Award” from DST-NSTMIS, SPAICS, Indore, in 2019, and the “Outstanding Scientist Award” at the 6th International Scientist Awards on Engineering, Science, and Medicine in 2020. He also received the “Distinguished Professor Award” from the Indian Pharmaceutical Association, MP State Branch, in 2021, and the “Best Academician Award” at the Indian Pharmacy Graduate Association, M.P. State International Conference in 2023.Sumel Ashique is Assistant Professor in the Department of Pharmaceutical Technology, Bharat Technology, Howrah, India. With five years of teaching experience, he has made notable contributions to his field. He has published more than 100 papers in reputable international and national journals. His expertise includes drug delivery, nanotechnology, and targeted treatment strategies. He also serves as a reviewer for several prestigious international journals. He holds five granted patents from IP Australia, India, and Canada. He has contributed to 20 book chapters and has edited 18 books.Mithun Bhowmick is Professor and Principal at the Bengal College of Pharmaceutical Sciences & Research in Durgapur, West Bengal, India. He has received numerous prestigious awards throughout his career. Dr. Bhowmick has actively participated in and presented research papers at various international and national conferences. He has published more than 50 research and review papers in esteemed national and international journals. His accomplishments include several patents from Australia, Germany, and India, as well as design patents and copyrights. Dr. Bhowmick is a reviewer for numerous pharmaceutical journals and is a lifetime member of several professional organizations, including the Association of Pharmaceutical Teachers of India (APTI), the Indian Pharmacy Graduates’ Association (IPGA), and the Institute of Scholars (InSc.). He is also a registered fellow member of the Centre for Education Growth and Research (CEGR) in New Delhi.

• AcknowledgmentPrefaceAbout the EditorsChapter 1 Prebiotics: General Overview, Characteristics, and Application in Health BenefitsAyush Madan, Rahul Kumar, Pranshul Sethi, and Debasis MitraChapter 2 Introduction to the Gut–Brain AxisAshish Garg, Abhavya Shukla, Sweta Garg, Prakash Pandey, Vishal Singh, and Gopal RaiChapter 3 Introduction and Overview of Prebiotics, Probiotics, and PostbioticsPhool Chandra, Nishat Fatma, and Neetu SachanChapter 4 Bidirectional Communication in the Gut–Brain AxisPriya Chaudhary, Divya Kumari, Apurva, Narotam Sharma, and Pracheta JanmedaChapter 5 Gut Dysbiosis and Its Impact on Neurological HealthHari Om, Kavita, and Pramod Kumar KushwahaChapter 6 Connection between Gut Microbiota and Neurodegenerative DiseasesAniruddha Sen, Vijay Singh, Bidisha Halder, Sapna Saini, Sumel Ashique, Radheshyam Pal, Sabina Yasmin, and Mohammad Yousuf AnsariChapter 7 Gut Microbiota in Mental Health DisordersSaikat Santra, Rajdip Goswami, Bhaskar Pal, Subhajit Das, and Ayan ChatterjeeChapter 8 Gut–Brain Axis and Autoimmune Diseases: Correlation between BothDevid Chutia, Jadab Rajkonwar, and Srijita ChakrabartiChapter 9 Signaling Events from the Gut: Regulate Brain Function and Its Link to Autoimmune DisordersGagandeep Kaur , Parul Sood , Shabnam, Rupesh K. Gautam, and Nitin JangraChapter 10 Role of Probiotics in Alzheimer’s Disease and Parkinson’s DiseaseMohsin Vahid Khan, Mohd Rumman, Anas Islam, Mohd Kamil Hussain, and Gulam RabbaniChapter 11 Role of Probiotics in Amyotrophic Lateral Sclerosis (ALS) and Huntington’s DiseaseMirunalini Gobinath, L Priyanka Dwarampudi, Shanmugam R, Subhajit Dutta, Parikshit Roychowdhury, and Swati Swagatika SwainChapter 12 Role of Probiotics in MS, Epilepsy, and SeizuresKajal Gurow, Deepak Chandra Joshi, Uttam Singh Baghel, and Lata BishChapter 13 Role of Probiotics in Anxiety and DepressionMirunalini G, L Priyanka Dwarampudi, Shanmugam R, Parikshit Roychowdhury, and Subhajit DuttaChapter 14 Role of Probiotics and Prebiotics in Ischemic Stroke in Connection with the Gut–Brain AxisAarti Gupta, and Alankar ShrivastavaChapter 15 Role of ProbioticsDivya Kumari, Ayush Madan, Priya Chaudhary, and Pracheta JanmedaChapter 16 Correlation between Gut Microbiome and Malnutrition and Other Factors in Neurological DisordersManikandan GurusamyChapter 17 Tools and Bioinformatic Approaches to Study Gut Microbiota and NeurodegenerationRideb Chakrabortya, Naureen Afrose, Pratibha Bhowmick, and Mithun BhowmickChapter 18 Brain–Gut Axis Focusing on High-Throughput Technologies Like Gene Sequencing, Brain Imaging, and MetabolomicsVaibhav Dagaji Aher, Abhishek Sharma, Simanchal Panda, Krishna Chandra Panda, and Pankaj SharmaChapter 19 Signaling Pathways and Gut–Brain Axis: Relationship in Neurological DisordersPapia Acharjee, Vishal Vikram Singh, Shambhu Kumar Prasad, Priyanka Thakur, and Arup AcharjeeChapter 20 Prebiotic as Functional Food in Neurological DisorderPankaj Sharma, Sarvesh Bhargava, Vinay Jain, Deepesh Parashar, and Wasim AkramChapter 21 Postbiotics and Psychobiotics: Therapeutic Interventions in Neurodegenerative DiseasesAnas Islam, Badruddeen, Mohammad Irfan Khan, Mohsin Vahid Khan, and Yusuf AsadChapter 22 Gut Microbiota-Derived Bacterial Metabolites: Role in Neurological DisordersKaran Goel, Isha Chawla, Garima, and Meenakshi DhanawatChapter 23 Therapeutic Applications of Prebiotics, Probiotics, and PostbioticsSurendra Agrawal, Pranita Jirvankar, Sunita Vaidya, Nikhita Chambhare, and Pravina GurjarChapter 24 Nanocarriers Encapsulated Polyphenols, Functional Foods to Modulate Gut Microbiota: In Neurological DisordersAmeya Sharma, Malkiet Kaur, Divya Dheer, Aditya Gautam, and Vivek PuriChapter 25 Probiotics as Nutraceuticals in Neurological DisordersM. Malarvannan, S. Bhanu Teja Naik, David Paul, Satheeshkumar Nanjappan, and V. RavichandiranChapter 26 Lifestyle and Environmental Factors: Impact on Gut Microbiota and Neurological DisorderPooja S Murkute, Saistha Anjum, S. Sowmiya, Arghya Paria, Sourabh Kosey, Naheed Mojgani, and Sumel AshiqueChapter 27 Prebiotics, Probiotics, and Postbiotics as a Complementary Therapy in the Management of Neurological Disorders: Clinical Trials and Case StudiesHeena¹, Priyanka Rana¹, Monika ¹, Tanzeer Kaur², Neelima Dhingra*Chapter 28 Application of Artificial Intelligence in Connection with Gut Microbiota to Detect Neurological DisordersN.L. Swathi, Kashif Raza Siddique, Habiba Babul, Pranjal. Kumar Singh, and Dinesh KumarChapter 29 Future Perspectives and Challenges of Probiotics, Prebiotics, and Postbiotics and Gut–Brain Axis in Neurodegenerative DisordersSamaresh Pal Roy, Sunil Kumar Kadiri, Suchismita Bhowmik, Vimal Patel, and Lokesh DebChapter 30 Regulatory Concern of Prebiotics, Probiotics, Postbiotics, and Market Growth in IndiaSoumik Bhattacharjee, Sumit Nandi, Dr Rana Dutta, Dr Amites Gangopadhyay, and Dr Kalyan Kumar SenIndex