Biotechnological Strategies for the Treatment of Gluten Intolerance

Mauro Rossi is Research Director at the Italian National Research Council (CNR)—Institute of Food Sciences (ISA) and Head of the Immunobiology Unit. He has 30 years of work experience in the field of the Biochemistry and Immunology of the small intestine. In the 1990s, he worked in the laboratories of Professor Auricchio (University “Federico II” of Naples, Italy), Noren (Panum Institute, Copenhagen, Denmark), Semenza (ETH, Zurich, Switzerland) on the biosynthesis of intestinal disaccharidases and lactose intolerance (adult-type hypolactasia), and Professor Londei (Kennedy Institute of Rheumatology, London, United Kingdom) on the cellular and molecular aspects of antigen-specific T-cell activation. His research focuses on the immunology of the small intestine, mainly on the mechanisms of tolerance to food antigens and on the development of microbiological and enzymatic strategies to downregulate the intestinal hypersensitivity to wheat gluten. He is also involved in basic and oriented applied research on probiotics.

• 1. Gluten intolerance: The triggering agents 2. Beyond the intestine 3. New dietary approaches 4. Non-dietary approaches

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