Biophysics of Tissue Self-Organization in Morphogenesis

Nyhet

The Role of Dynamics Along the Biointerface

Häftad, Engelska, 2026

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Biophysics of Tissue Self-Organization in Morphogenesis: The Role of Dynamics Along the Biointerface delves into the interactions between tissue and the extracellular matrix. It explores the fundamentals of cell self-rearrangement and the interrelation between biological mechanisms and physical principles responsible for tissue self-organization. The book examines modeling approaches to tissue self-organization and the application of engineering principles to solve medical problems. It also discusses tools, applications, and medical implications, particularly in embryo development, wound healing, and cancerous diseases, concluding with future developments.

Covering subcellular to supracellular levels, this book is an interdisciplinary guide for researchers in cell biology, biophysics, developmental biology, and more.

Describes biological mechanisms of cell self-rearrangement, from subcellular to supracellular levels
Explores mathematical modeling approaches of tissue self-organization
Considers engineering principles to solve biological and medical problems related to tissue self-organization
Discusses tissue self-organization within various in vivo and in vitro organoid systems

Produktinformation

Utgivningsdatum2026-04-22
Mått191 x 235 x 18 mm
Vikt450 g
FormatHäftad
SpråkEngelska
Antal sidor334
FörlagElsevier Science
ISBN9780443300486

Tillhör följande kategorier

Tillämpad fysik inom Naturvetenskap och teknik
Biokemi inom Naturvetenskap och teknik
Biologi inom Naturvetenskap och teknik

Dr. Ivana Pajic-Lijakovic is a scientific advisor at the Department of Chemical Engineering, University of Belgrade, Serbia. Her research interest is related to biological physics, biorheology and biomechanics. She has previously worked as a guest editor for various special issues and has published a book with Elsevier titled: ‘’Viscoelasticity and Collective Cell Migration: An Interdisciplinary Perspective Across Levels of Organization (2021). Her research has been published in multiple leading international peer-reviewed journals.

Section 1: Tissues self-organisation in morphogenesis1. Cell adhesion: Common mechanisms and physical principles2. Analysis of the effect of cell movement on gene expression dynamics in development3. Force transmission across scales: Examples and measuring methods4. The impact of air pollution on the tissue self-organisation within co[1]cultured lung systemsSection 2: Physics of tissue self-organisation from subcellular to supracellular levels5. How physical cues guide cell collectives, from local adhesion to global force transmission6. Cellular death and division events at tissue interfaces: A chicken-or[1]the-egg situation7. Active Nematics: Exploring the Interplay between structure and dynamics in cell cultures8. The dynamics along the epithelial-cancer bio-interface within co[1]cultured cell spheroids: Physical aspects9. Dynamical interplay at the interfaces of cancer cells, immune cells and stromal cells in the extracellular space of artificial model systems and tissues10. Techniques development to quantify cell-scale dynamic mechanical interactions in extracellular matrices of tissuesSection 3: Modeling of the tissue self[1]organization11. Mathematical modelling approaches to collective cell movement: Leader vs. follower cellsSection 4: Engineering of human tissues12. Engineering of human tissues13. Conclusion and outlook