Bioorganic Chemistry

Highlights and New Aspects

Häftad, Engelska, 1999

Av Diederichsen, Lindhorst, Ulf Diederichsen, Thisbe K. Lindhorst, B. Westermann, Ludger A. Wessjohann, Germany) Diederichsen, Ulf (Technical University Munich, Garching, Germany) Lindhorst, Thisbe K. (University of Hamburg, The Netherlands) Wessjohann, Ludger A. (Vrije Universiteit Amsterdam

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The understanding of (patho)physiological processes - the biosynthesis of biomolecules such as enzymes, nucleic acids, and secondary metabolites; the pathways of signaltransduction; or the function of pharmaceutical agents - is of increasing importance not only for drug research but also for the development of new synthetic methods in organic chemistry and biochemistry. In a truly interdisciplinary way bioorganic chemistry unites the central questions of biochemistry, medicinal chemistry, organic chemistry, and spectroscopy. This book fills a void in this rapidly growing field of chemistry and gives a thorough yet understandable introduction for advanced students and researchers alike. Contributions of more than sixty scientists provide a topical overview of recent advances in: drug development based on natural products; the biosynthesis, activity, and application of enzymes; carbohydrates; peptides; nucleic acids; analytical methods in bioorganic chemistry. This book will be an appetizer for all - students and researchers alike - seeking orientation in this fascinating field of chemistry.

Produktinformation

Utgivningsdatum1999-10-19
Mått172 x 245 x 23 mm
Vikt765 g
FormatHäftad
SpråkEngelska
Antal sidor456
FörlagWiley-VCH Verlag GmbH
ISBN9783527296651

Tillhör följande kategorier

Analytisk kemi inom Naturvetenskap och teknik
Biologi inom Naturvetenskap och teknik
Biokemi inom Naturvetenskap och teknik
Organisk kemi inom Naturvetenskap och teknik

>Ulf Diederichsen studied Chemistry in Freiburg, Germany, with a diploma work in organic synthesis and completed his Ph.D. in 1993 under the supervision of Albert Eschenmoser at the ETH Zürich working on homo- and glucose-DNA. Following postdoctoral work on radical chemistry at the University of Pittsburgh, USA, in the group of Dennis Curran, he gained his habilitation at the Technical University Munich, Germany, with Horst Kessler as mentor. In 1999, he was appointed professor of Organic Chemistry at the University Würzburg, Germany, until joining the Georg-August-University in Göttingen, Germany, in 2001 as full professor of Organic Chemistry. He was visiting professor at the LMU Munich and Goering Visiting Professor at the University of Wisconsin, USA. In 1999 he got the Karl Winnacker stipend and Hellmut-Bredereck award and is an ordinary member of Göttingen Academy of Sciences and Humanities since 2012

DRUGS AND SEARCH FOR LEAD STRUCTURESMarine AlkaloidsLeukotriene DerivatesDiazoketones for the Synthesis of Beta-LactamsSelenium Compounds in Biochemical OxidationsGalaktophingolipid, etcENZYMOLOGYEnzyme Catalyzed Diels-Alder ReactionsEnzymatic Halogenation in BacteriaBiotransformations in the Stereoselective Synthesis of Cyclophanes, etcCARBOHYDRATESMannosid ClustersGlycoconjugates in Cancer Therapy, etcPEPTIDESCyclodepsipeptidesSynthetic Adrenaline and Peptide ReceptorsSubstituted and Beta-Amino Acids as Building Blocks for Peptide MimeticsCarbohydrate-Protein Interactions, etc.NUCLEIC ACIDSReparing DnaIn Vitro SelectionStudies on Hairpin RibozymesNew Pna Buiding Block for Antisense Research, etc.BIOCHEMISTRYActivity of Neuropeptide YOligosaccharide AntibioticsBiosynthesis of Plant XanthonesManipulating Intracellular Signal TransductionsMethyl-Transfer Reactions, etc.SYNTHETIC AND ANALYTICAL METHODSConstitutional Assignment of Marine Natural ProductsRadical Induced Reactions in Biological SystemsMultivariate Analysis of Biotransformations, etc.

Rezensionen: "...bietet dieses Buch einen guten Überblick und Einstieg sowohl von chemischer als auch von biologischer Seite...Für alle, die Interesse an spannenden neuen Themen wie enzymatische Diels-Alder Reaktionen oder die Synthese von Oligonucleotiden mit Polypeptid Rückgrat anstatt des Zucker/Phosphat Rückgrats werden an diesem Buch ihre Freude haben." KVV d. Fachschaft Biologie-und Chemiewissenschaften Potsdam