This book presents a comprehensive exploration of advancements in the fields of biology, medicine and agriculture, illuminating the intersection of STEM with health, diseases, and sustainability. It is organized into six sections. The first section introduces foundational concepts on the development of biomedical innovations. Subsequent chapters in Section II delve into medical devices, detailing groundbreaking tools such as steerable catheters, blood monitors, and advanced imaging technologies. Materials and implants such as scaffoldings for tissue generation and genetically manufactured heart are covered in Section III. The next section on pharmaceutics covers critical innovations in vaccines, antibiotics, and gene engineering, highlighting their roles in addressing global health challenges. In the fifth section, the author emphasizes the importance of maintaining a healthy and sustainable world, discussing preventative measures against obesity, addiction, and environmental degradation, global warming and extreme weathers. The final section examines industrial developments within five biomedical sectors—medical devices, pharmaceutical, agriculture, environmental and sustainable industries—providing insights into their innovations and the challenges they face.Throughout the text, readers will discover how these biomedical innovations are developed and applied to diagnose health issues, treat diseases, and enhance the well-being of individuals and communities. In this context, the book is not just a catalog of technological achievements; it is a call to action for future generations to engage with and contribute to the evolving landscape of biomedical science and engineering.