Del 0 - Methods in Molecular Biology

Biological Networks and Pathway Analysis

Häftad, Engelska, 2018

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In this volume, expert practitioners present a compilation of methods of functional data analysis (often referred to as “systems biology”) and its applications in drug discovery, medicine, and basic disease research.

Produktinformation

Utgivningsdatum2018-08-03
Mått178 x 254 x 29 mm
Vikt974 g
FormatHäftad
SpråkEngelska
SerieMethods in Molecular Biology
Antal sidor509
FörlagHumana Press Inc.
ISBN9781493983728

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A Practical Guide to Quantitative Interactor Screening with Next-Generation Sequencing (QIS-Seq).- sbv IMPROVER: Modern Approach to Systems Biology.- Mathematical Justification of Expression-Based Pathway Activation Scoring (PAS).- Bioinformatics Meets Biomedicine: OncoFinder, a Quantitative Approach for Interrogating Molecular Pathways Using Gene Expression Data.- Strategic Integration of Multiple Bioinformatics Resources for System Level Analysis of Biological Networks.- Functional Analysis of OMICs Data and Small Molecule Compounds in an Integrated “Knowledge-Based” Platform.- Extracting the Strongest Signals from Omics Data: Differentially Expressed Pathways and Beyond.- Search for Master Regulators in Walking Cancer Pathways.- Mathematical Modeling of Avidity Distribution and Estimating General Binding Properties of Transcription Factors from Genome-Wide Binding Profiles.- A Weighted SNP Correlation Network Method for Estimating Polygenic Risk Scores.- Analysis of cis-Regulatory Elements in Gene Co-Expression Networks in Cancer.- Applying Association Rule Mining Techniquest to Predict Procaryotic Metabolic Pathways.- ArrayTrack: An FDA and Public Genomic Tool.- Identification of Transcriptional Regulators of Psoriasis from RNA-Seq Experiments.- Comprehensive Analyses of Tissue-Specific Networks with Implications to Psychiatric Diseases.- Semantic Data Integration and Knowledge Management to Represent Biological Network Associations.- Knowledge-Based Compact Disease Models: A Rapid Path from High-Throughput Data to Understanding Causative Mechanisms for a Complex Disease.- Pharmacologic Manipulation of Wnt Signaling and Cancer Stem Cells.- Functional Network Disruptions in Schizophrenia.