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Khemraj Deshmukh, Arun Kumar Singh, Gourav Singh, Jitendra Kumar - Biological Fluid-Mediated Transport Mechanisms for Targeted Drug Delivery in Next-Generation Cancer Immunotherapy, Häftad

Häftad, Engelska, 2026

Biological Fluid-Mediated Transport Mechanisms for Targeted Drug Delivery in Next-Generation Cancer Immunotherapy

Av Khemraj Deshmukh, Arun Kumar Singh, Gourav Singh, Jitendra Kumar

3049 kr

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Beskrivning
Biological Fluid-Mediated Transport Mechanisms for Targeted Drug Delivery in Next-Generation Cancer Immunotherapy addresses the critical need for innovative therapeutic platforms that improve efficacy and reduce toxicity in cancer treatment. The volume explores how natural biofluids and derived carriers, like exosomes and extracellular vesicles, can serve as highly biocompatible vehicles for delivering immunotherapeutics. It emphasizes their roles in overcoming barriers such as immune evasion, rapid clearance, and systemic side effects, while also leveraging biofluid signatures for real-time diagnostics through liquid biopsies. The book encompasses topics from the composition and biomolecular content of biofluids to the engineering strategies for functionalization, targeting, and controlled release, integrating cutting-edge nanotechnologies and microfluidics.

This reference book supports the advancement of next-generation precision cancer immunotherapies by providing insights into biofluid dynamics, bioresponsive carriers, and personalized approaches. It bridges basic science with translational potential, fostering innovation in nanomedicine, immunology, and biomedical engineering, and aims to accelerate the clinical impact of biofluid-inspired drug delivery systems.

  • Explores biofluid-based platforms to optimize cancer immunotherapy
  • Integrates interdisciplinary perspectives from nanotechnology, immunology, and engineering
  • Highlights diagnostic and therapeutic roles of biofluids and extracellular vesicles
  • Discusses engineering strategies for functionalizing biofluid carriers
  • Addresses regulatory, scalability, and translational challenges
Produktinformation
  • Utgivningsdatum: 2026-10-30
  • Mått: 191 x 235 x undefined mm
  • Vikt: 450 g
  • Format: Häftad
  • Språk: Engelska
  • Antal sidor: 424
  • Förlag: Elsevier Science
  • ISBN: 9780443516009
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Mer information

Dr. Khemraj Deshmukh is a dedicated researcher and academician in the field of Biomedical Engineering with over more than 8 years (6 years of teaching, 1.5 years of research, and 2.5 years of industry experience). He earned his Ph.D. from the National Institute of Technology, Raipur, with his doctoral research focusing on the numerical study and evaluation of poly-electrolyte complex scaffolds under cryogenic conditions. His expertise spans computational dynamics, biomaterials, cryogenic heat transfer, cell culture fluid dynamics, soft materials, 3D bioprinting, and automation and control. He has published extensively in reputed SCI and Scopus-indexed journals, contributing over 30 research papers, book chapters, and conference proceedings. Notable works include studies on scaffold degradation undercryogenic environments, flow dynamics in microchannels, and nanotechnology-based drug delivery. His interdisciplinary research also extends to artificial intelligence applications in healthcare and biomedical signal processing. In addition, he has authored several book chapters with IOP Publishing and holds both utility and design patents, including innovations such as a programmable cryogenic chamber and advanced biomedical devices. Dr. Deshmukh has successfully supervised 9 M.Tech dissertations and is currently guiding a 1 Ph.D. scholar. He has led projects funded by national agencies (40 lakh), including the fabrication of a 3D printer–based rotatory bioreactor for vascular tissue engineering. His achievements include the design and validation of a functional 3D bioprinter and development of compact cryogenic storage systems. A member of professional bodies and an active participant in international conferences, he continues to make impactful contributions to biomedical engineering research and education.Arun Kumar Singh is Assistant Professor in the Department of Pharmacy at the University School of Pharmaceutical Sciences, Rayat Bahra University, Sahauran, India. His research interests include nano-formulation, cancer biology, and neuroscience, alongside digital and computational approaches such as machine learning, artificial intelligence, big data analytics, blockchain, and the Internet of Things. He has contributed academic books, book chapters, and review articles in pharmaceutical sciences and healthcare technology, with a focus on interdisciplinary approaches that integrate pharmaceutical research with emerging digital technologies.Dr. Gourav Singh is an Assistant Professor at Amity Institute of Pharmacy, India, and a researcher in medicinal chemistry with a keen focus on neurodegenerative diseases, especially Alzheimer's disease (AD). His research has centered on the rational design, synthesis, and biological evaluation of small molecules aimed at therapeutic intervention. Dr. Singh has co-authored research articles in a number of journals. With a strong interdisciplinary foundation spanning organic synthesis, computational drug design, and biological validation, Dr. Singh effectively bridges chemistry and neuropharmacology. His work significantly advances translational drug discovery efforts targeting neurodegenerative disorders.Dr. Jitendra Kumar (Ph.D., Biomedical Engineering) is currently serving as an Assistant Professor in the Department of Biomedical Engineering at B.V. Raju Institute of Technology, Narsapur (Hyderabad). He earned his doctoral degree in Biomedical Engineering from the National Institute of Technology Raipur, India, in 2024, with his thesis focused on the Design and Analysis of Bio-inspired Porous Based Hip Implant Component. He holds an M.Tech. in Instrumentation and Control Engineering from VIT Pune (2011), a B.E. in Biomedical Engineering from NIT Raipur (2007), and a PGDMM in Material Management from Annamalai University (2019). With more than eight years of academic and industry experience, including roles as Biomedical Engineer under the National Health Mission and Assistant Professor at CSVTU Bhilai and SSTC Bhilai, His research expertise in finite element analysis, orthopaedic implants, 3D printing, porous scaffold design, computational fluid dynamics, biomaterials, tissue engineering, and biomedical signal processing. His research contributions include several peer-reviewed journal publications, conference papers, and three patents filed/granted in the domain of biomedical implants and medical devices. He is proficient in advanced computational and experimental tools such as ANSYS (Structural & CFD), MATLAB, Materialise Mimics, 3D Printing, SEM, TEM, and Micro-FTIR. Dr. Kumar is a lifetime member of the Biomedical Engineering Society of India (LM-1535) and has actively participated in specialized training programs on organ printing, biomaterials, and advanced microscopy techniques. He has contributed significantly to the design and analysis of orthopedic and scaffold structures inspired by triply periodic minimal surfaces, balancing mechanical strength with additive manufacturability.

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