Biofilm Associated Antimicrobial Resistance and Its Recovery

Dibyajit Lahiri is Assistant Professor in the Department of Biotechnology, University of Engineering & Management, Kolkata. His research is precisely on biofilm isolated from human prosthesis and its inhibition by various novel phyto and nano compounds. He is keen to explore the molecular mechanism behind the removal of biofilm by natural compounds. His research area also encompasses computational drug development by using bioinformatics. His work is regularly presented before and appreciated by a number of experts of national and international repute. He is the editor of various international journals. He is a life member of the Indian Science Congress Association and Institution of Engineers (India). He has also edited books for Springer Nature and Elsevier.Moupriya Nag is Assistant Professor in the Department of Biotechnology, University of Engineering & Management, Kolkata. Her research interests include single molecule Biophysics of protein unfolding/refolding and protein aggregation kinetics and its mechanism of action especially the amyloid proteins in neurodegenerative disorders. Her recent research focuses on functional amyloids in bacteria and their relation in forming biofilms. Her work deals with developing novel antimicrobial and anti-biofilm compounds from natural sources including plants, microbes and green synthesized nanoparticles. She has about six years of teaching experience in Biophysics, Bioinformatics, Bioprocess and Biotechnology, Enzyme Technology, Computing, Molecular Modeling and Drug Design. She has also published many research articles in peer-reviewed international journals and authored or co-authored numerous book chapters. She is also a member of many scientific societies such as the Indian Biophysical Society and Indian Science Congress Association. Rina Rani Ray is Associate Professor in the Department of Biotechnology, Maulana Abul Kalam Azad University of Technology, West Bengal. Her research focusses on the diverse field of microbial biotechnology. She has worked in academia and research for more than 25 years in several institutes of repute. She started her research career in the field of microbial enzyme technology. She successfully completed a number of research projects funded by different sponsoring agencies such as UGC, DST and DRDO and is working on a project sponsored by DBT, WB. She has published around 80 research papers in various peer-reviewed national and international journals and is on the editorial boards and a regular reviewer of many journals. At present her research group is working on the positive and negative aspects of bacterial biofilm. She is a member of various scientific associations and was nominated fellow of the Zoological Society, India and the Academy for Environment and Life Sciences, India. She has also edited books for Springer Nature.Sougata Ghosh is Associate Professor and Research Co- ordinator in the Department of Microbiology, School of Science, RK University, India. He obtained his BSc., MSc. and Ph.D. in Microbiology from Savitribai Phule Pune University, India. He is also Visiting Professor at the Department of Physics, Faculty of Science, Kasetsart University, Bangkok, Thailand and Department of Chemical Engineering, Northeastern University, Boston, USA. He was principle investigator of the Department of Biotechnology (DBT), Government of India funded Foldscope Research Project. He has filed three patents on novel nanodrugs and published more than 70 highly cited research articles in various international journals such as the International Journal of Nanomedicine, Journal of Nanobiotechnology, Journal of Nanomaterials, Journal of Nanoscience and Nanotechnology. He has 4077 citations, h-index 33 and i10 index 70. He has written one book entitled Dioscorea bulbifera: A model system in nanobiotechnology and medicine, which is a frequently consulted, voluminous and comprehensive report on traditional medicinal plants. He has edited eight books and contributed to 150 book chapters. As speaker he has addressed numerous international conferences, the most notable being IJAS- 2019 and 2017 at Harvard University; ITNANO, Northeastern University, Boston; ASM Biodefense, Washington D.C.; Nano- Bio- Med 2013, Trieste, Italy; and BioMicroWorld2013, Madrid, Spain. He is a reviewer for various reputed journals such as Nanoscale, Journal of Photochemistry & Photobiology, B: Biology, Journal of Diabetes Research, International Journal of Advances in Engineering Research, International Journal of Research in Science and Technology, Chemotherapy Research and Practice, Journal of Nanomedicine & Biotherapeutic Discovery, Journal of Nanomedicine and Nanotechnology, Applied Nanoscience and Arabian Journal of Chemistry (Elsevier). He is a life member of the Association of Microbiologists of India (AMI). His area of research consists of but is not limited to nanomedicine, microbial metabolism, bioprospecting, bioremediation, biofilms, cancer and diabetes.

• IntroductionBiofilm Formation and Metabolomic RegulationSusceptibility Testing for the Determination of Biofilm Associated ResistanceNutritional and Stress Responses Resulting in the Development of AMREfflux Pumps and Their Role in the Development of Resistance in BiofilmGenetic Diversity Resulting in the Development of AMRMultispecies Interactions Resulting in the Development of Antimicrobial ResistanceNanotechnology Approaches to Treating Antimicrobial Resistant Infections Caused by Biofilms: Research Needs for Translation from In Vitro to In Vivo ApplicationsAntimicrobial Peptides for Treating Biofilm Associated InfectionsEnzymatic Dispersion of Biofilms: Applications, Challenges and QuantificationCRISPR/Cas Therapeutics in the Inhibition of BiofilmSmall Molecule Associated Inhibition of Metabolic Pathways in BiofilmBacteriophage Associated Inhibition of Biofilm: A ReviewNanoparticle Associated Inhibition of BiofilmBiofilms: Formation, Regulation, and Detection