Biochemistry of Atherosclerosis

Dr. Sukhinder K. Cheema is Associate Professor of Biochemistry, Memorial University of Newfoundland, Canada. She has worked as a Research Scientist with the Nova-Husky Research Corporation in Alberta, Canada. She is currently researching the molecular mechanisms of cholesterol ester transfer protein regulation by dietary fats and hormones. She also researches the regulation of genes involved in cholesterol metabolism by hormone factors, the molecular basis of diabetes-accelerated atherosclerosis, and the mechanisms of lipid abnormalities caused by protease inhibitors.

• The role of HDL in the prevention of atherosclerosis.- Cholesterol breakdown and the significance in atherosclerosis.- Triacylglycerol hydrolase, VLDL assembly and development of atherosclerosis.- Regulation of Hepatic Production of Lipoproteins Containing Apolipoprotein B and the significance in atherosclerosis.- Dyslipidemia and thrombogenesis.- Mouse models of Diabetes and Atherosclerosis.- Role of the unfolded protein response in atherosclerosis: a potential unifying theory of atherogenesis.- SR-BI, reverse cholesterol transport and atherogenesis.- Hypertension and atherosclerosis.- Dietary fats, transcription factors and heart health.- Dietary fatty acid intake and stroke.- Homocysteine metabolism and atherosclerosis.- Vitamin supplements in preventing atherosclerosis.- Oxidized lipids and heart disease.- Reverse cholesterol transport and prevention of atherosclerosis.- Homocysteine, diabetes mellitus and atherosclerosis.- Treating low HDL-From bench to bedside.- Atherosclerosis is an infectious disease.