Bioassay Methods in Natural Product Research and Drug Development

This volume contains the proceedings from the Phytochemical Society of Europe's symposium on this topic, held August 24-27, 1997, in Uppsala, Sweden. In it, leading academic and industrial scientists discuss methods for assaying natural products to find new structure-activity relationships. Of key importance in this process is the availability and reliability of specific bioassay methods, but chapters also discuss chemical and biological diversity and how to dereplicate natural product extracts to increase efficiency in lead discovery. Anti-tumour, HIV-inhibitory, antiprotozoal, anti-infective and immunomodulatory natural products are discussed. Various industrial projects are presented. The volume seeks to bridge the gap between academic and industrial research, and should be useful reading in drug companies and faculties of pharmacy, as well as serving scientists in pharmacognosy, pharmacology, phytochemistry, natural products and drug discovery.