Better Hearing with Cochlear Implants

Blake S. Wilson is the co-director (with Debara L. Tucci, MD) of the Duke Hearing Center and is an adjunct professor in two departments at Duke, Surgery and Electrical Engineering. He is also the chief strategy advisor for MED-EL GmbH in Innsbruck, Austria, and a senior fellow emeritus of the Research Triangle Institute in the Research Triangle Park, NC, USA. He has been involved in the development of the cochlear implant for the past three decades, and is the inventor of many of the signal processing strategies used with the present-day devices. He has served as the principal investigator for 25 projects, including 13 projects for the NIH. Professor Wilson has been the guest of honor at 12 international conferences and a keynote or invited speaker at more than 180 conferences. Michael F. Dorman is a professor in the Department of Speech and Hearing Science and in the Program Linguistics at Arizona State University. He is a Fellow of the Acoustical Society of America and is the author of over 150 publications in areas including: (i) speech perception by infants, adults, hearing-impaired listeners, and listeners fit with cochlear implants; (ii) cortical lateralization of function; and (iii) neural plasticity. His work on cochlear implants has been supported continuously by the NIH since 1989.

• Acknowledgments Dedication Chapter 1 Overview PART I Design and Evaluation of Novel Processing Strategies Introduction Chapter 2 Comparison of Analog and Pulsatile Coding Strategies for Multichannel Cochlear Prostheses Chapter 3 New Levels of Speech Reception with Cochlear Implants Chapter 4 Evaluation of Alternative Implementations of the Continuous Interleaved Sampling (CIS), Interleaved Pulses (IP), and Peak Picker (PP) Processing Strategies Chapter 5 Comparison of Compressed Analog (CA) and Continuous Interleaved Sampling (CIS) Processors in Tests with Seven Ineraid Subjects Chapter 6 Evaluation of Other Promising Strategies Chapter 7 Completion of "Poor Performance" Series Chapter 8 Auditory Brainstem Implant (ABI) Studies Chapter 9 Virtual Channel Interleaved Sampling (VCIS) Processors: Initial Studies With Subject SR2 Chapter 10 Identification of Virtual Channels on the Basis of Pitch Chapter 11 Further Evaluation of VCIS Processors Chapter 12 Design for an Inexpensive but Nonetheless Highly Effective Cochlear Implant System Chapter 13 22-Electrode Percutaneous Study: Results for the First Five Subjects PART II Electrical Stimulation on Both Sides With Cochlear Implants Introduction Chapter 14 Speech Reception With Bilateral Cochlear Implants Chapter 15 Sensitivities to Interaural Timing Differences Chapter 16 Pitch Ranking of Electrodes for 22 Subjects With Bilateral Cochlear Implants PART III Combined Electric and Acoustic Stimulation (EAS) of the Auditory System Introduction Chapter 17 Psychophysical Studies Relating to Combined EAS Chapter 18 Speech Reception With Combined EAS PART IV Representations of Temporal Information With Cochlear Implants Introduction Chapter 19 Temporal Representations With Cochlear Implants Chapter 20 Strategies for the Repair of Deficits in Temporal Representations With Cochlear Implants Chapter 21 High Rate Studies, Subject SR2 Appendix A. Partners in Research Appendix B. Topics and Authors for the RTI Progress Reports Appendix C. Publications Resulting from the RTI Projects Appendix D. Contents of the RTI Progress Reports Sorted by Topic References Index

Mario Svirsky, PhD & Noel L. Cohen, Professor of Hearing Science & Otolaryngology/Neural Science, Vice-Chairman for Research, NYU Langone Medical Center, Ear & Hearing (Vol. 35, No. 1), (Jan. 2014): "Cochlear implants remain the only examples to date of an electronic device successfully replacing a human sensory end organ, and they represent one of the major medical advances of the twentieth century. This has been recently recognized by the Lasker Foundation by giving the prestigious Lasker-DeBakey Clinical Medical Research Award to Blake Wilson [author of this text], Graeme Clark, and Ingeborg Hochmair - The Lasker Awards are second only to the Nobel Prize in Physiology or Medicine for honoring advances in medicine and medical science... One of the Lasker awardees, Blake Wilson, and Michael Dorman (who is another pioneer and major contributor to the development of cochlear implant technology) describe the body of research and development work done at Research Triangle Institute (RTI) between 1983 and 2006. This work was largely funded by a series of contracts from the National Institute of Health's Neural Prostheses Program. One important characteristic of [the program] was that a quarterly progress report (QPR) was required. These QPRs were for many years one of the best-kept secrets in the cochlear implant field... [In] the publication of Better Hearing with Cochlear Implants - information is carefully organized according to theme and topic. The first part is about design and evaluation of novel processing strategies, and it includes information about the initial development of the CIS speech-processing strategy...Part two covers bilateral cochlear implant studies and focuses on the study of sensitivity to interaural timing differences as well as pitch ranking across the two electrode arrays. The third part examines combined electric and acoustic stimulation of the auditory system...The fourth and final part presents studies of the representation of temporal information with cochlear implants and the ways in which such representations might be improved by appropriate adjustments in simulation strategy. As will become clear to the reader, the RTI group pioneered many of the approaches described in the book. The book is engaging, clear, and very well written. It is obvious that a substantial amount of reflection and effort went into preparing the book, this was not at all a simple but massive "cut-and-paste" exercise from the QPRs. The authors present much information from the QPRs, but they also provide appropriate historical and technical context... Besides the technical information, readers will find the book interesting as an important contribution to the study of cochlear implant research history...I highly recommend this book to any reader with a personal or professional interest in cochlear implants, either from a historical perspective of a strictly technical perspective." David Selvadurat, GBPNT Consulcant, St Georges Hospital Cochlear Implant Programme, Tooting, UK, ENT & audiology news, Vol 23 No 2, (May/June 2014): " - It is a unique insight into the painstaking efforts that allowed the development of successful speech coding strategies, and also clearly shows the pivotal role that the RTI had in making these advances possible - In most chapters details of the experimental protocols and the individual results of the study subjects are recorded, along with a succinct and accessible discussion - The chapters dealing with general developments and current issues are very useful for those seeing and advising patients on these areas. Overall the book represents a very useful reference that all implant centres should have access to. It also is a very reasonable investment for those wishing to begin to understand the theories and developments behind the main speech processing strategies in use today. It fulfills its purpose well." Y Ramakrishnan, The Journal of Laryngology & Otology: "This book focuses on studies related to cochlear implants (and to a lesser extent auditory brainstem implants) performed at the Research Triangle Institute over two decades. By doing so, it provides the reader with an insight into how this field has evolved, culminating in the modern cochlear implant (CI) - A detailed analysis of each subject and processor type is presented very clearly, using various figures - This book beautifully distils the experience at the Research Triangle Institute."