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Del i serien Chapman & Hall/CRC Biostatistics Series

Bayesian Methods in Pharmaceutical Research

Häftad, Engelska, 2021

AvEmmanuel Lesaffre,Gianluca Baio,Bruno Boulanger

949 kr

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Since the early 2000s, there has been increasing interest within the pharmaceutical industry in the application of Bayesian methods at various stages of the research, development, manufacturing, and health economic evaluation of new health care interventions. In 2010, the first Applied Bayesian Biostatistics conference was held, with the primary objective to stimulate the practical implementation of Bayesian statistics, and to promote the added-value for accelerating the discovery and the delivery of new cures to patients.This book is a synthesis of the conferences and debates, providing an overview of Bayesian methods applied to nearly all stages of research and development, from early discovery to portfolio management. It highlights the value associated with sharing a vision with the regulatory authorities, academia, and pharmaceutical industry, with a view to setting up a common strategy for the appropriate use of Bayesian statistics for the benefit of patients. The book covers:Theory, methods, applications, and computingBayesian biostatistics for clinical innovative designsAdding value with Real World EvidenceOpportunities for rare, orphan diseases, and pediatric developmentApplied Bayesian biostatistics in manufacturingDecision making and Portfolio management Regulatory perspective and public health policies Statisticians and data scientists involved in the research, development, and approval of new cures will be inspired by the possible applications of Bayesian methods covered in the book. The methods, applications, and computational guidance will enable the reader to apply Bayesian methods in their own pharmaceutical research.

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