Basic Science of Oncology, Sixth Edition

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• 1. Introduction to Cancer Biology 2. Methods of Molecular Analysis 3. New: Epigenetics and principles of genome regulation4. Cancer Epidemiology 5. Chemical Carcinogenesis 6. Cellular Signaling Pathways 7. Oncogenes and Tumor-Suppressor Genes 8. Cell Proliferation and Death 9. Genomic Stability and DNA Repair 10. Tumor Progression and Metastasis 11. New title: Tumor Environment (formerly Angiogenesis) .12. Tumor Growth and Metabolism 13. Heterogeneity in Cancer: The “Cancer Stem Cell” Hypothesis 14. Imaging in Oncology 15. Molecular and Cellular Basis of Radiotherapy 16. Tumor and Normal Tissue Response to Radiotherapy 17. Discovery and Evaluation of Anticancer Drugs 18. Anticancer chemotherapy, pharmacology and mechanisms ofresistance19. New: Targeted cancer diagnosis and treatment20. Hormones andCancer 21. The Immune System and Immunotherapy . 22. Guide to Clinical Studies

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