Del 113 i serien Annals of the New York Academy of Sciences

Barriers and Channels Formed by Tight Junction Proteins I, Volume 1257

Häftad, Engelska, 2012

1 869 kr

Beställningsvara. Skickas inom 11-20 vardagar. Fri frakt för medlemmar vid köp för minst 249 kr.

Tight junctions between epithelial and endothelial cells form selective barriers and paracellular channels and regulate paracellular transport of solutes, immune cells, and drugs. More specifically, tight junctions consist of proteins that laterally interconnect neighboring cells of epithelia and endothelia. Certain proteins seal the tight junction, so that a nearly impermeable barrier develops, whereas others form channels that allow for permeation between the cells. Recent investigations have focused on tight junction proteins, belonging to the claudin family (claudins-1 to -27 in humans) and the newly defined group of TAMP (three proteins: occludin, Marvel-D2, and tricellulin). Barriers and Channels Formed by Tight Junction Proteins I showcases work in this area clustered around three major themes: the molecular properties of tight junctions, for example, the role of the claudin family of proteins and the formation of ion and charge-selective channels; the regulation of tight junction and barrier functions via genetic mechanisms and scaffold protein mediation; and the functional role of the tight junction in various tissues, such as the skin, lungs, endothelia, and nervous systemNOTE: Annals volumes are available for sale as individual books or as a journal. For informatio.n on institutional journal subscriptions, please visit http://ordering.onlinelibrary.wiley.com/subs.asp?ref=1749-6632&doi=10.111/(ISSN)1749-6632.ACADEMY MEMBERS: Please contact the New York Academy of Sciences directly to place your order (www.nyas.org). Members of the New York Academy of Science receive full-text access to the Annals online and discounts on print volumes. Please visit http://www.nyas.org/MemberCenter/Join.aspx for more information about becoming a member.

Produktinformation

Utgivningsdatum2012-07-10
Mått178 x 254 x 10 mm
Vikt454 g
FormatHäftad
SpråkEngelska
SerieAnnals of the New York Academy of Sciences
Antal sidor252
FörlagJohn Wiley and Sons Ltd
ISBN9781573318730

Tillhör följande kategorier

Kemi inom Naturvetenskap och teknik
Klinisk medicin och internmedicin inom Medicin
Biologi inom Naturvetenskap och teknik

1. Perspectives on tight junction researchJörg-Dieter Schulzke, Dorothee Günzel, Lena J. John, and Michael FrommMolecular properties of the tight junction20. Charge-selective claudin channelSusanne M. Krug, Dorothee Günzel, Marcel P. Conrad, In-Fah M. Lee, Salah Amasheh, Michael Fromm, and Alan S. L. Yu29. Claudin-derived peptides are internalized via specific endocytosis pathwaysDenise Zwanziger, Christian Staat, Anuska V. Andjelkovic, and Ingolf E. Blasig38. A phosphorylation hotspot within the occluding C-terminal domainMax J. Dörfel and Otmar Huber45. Determinants contributing to claudin ion channel formationAnna Veshnyakova, Susanne M. Krug, Sebastian L. Mueller, Jörg Piontek, Jonas Protze, Michael Fromm, and Gerd Krause54. Lipolysis-stimulted lipoprotein receptor: a novel membrane protein of tricellular tight junctionsMikio Furuse, Yukako Oda, Tomohito-Higashi, Noriko Iwamoto, and Sayuri Masuda59. Overexpression of claudin-5 but not claudin-3 induces formation of trans-interaction-dependent multilamellar bodiesJan Rossa, Dorothea Lorenz, Martina Ringling, Anna Veshnyakova, and Joerg Piontek67. Association between segments of zonula occludens proteins: live-cell FRET and mass spectrometric analysisChristine Rueckert, Victor Castro, Corinna Gagell, Sebastian Dabrowski, Michael Schümann, Eberhard Krause, Ingolf E. Blasig, and Reiner F. Haseloff77. Dynamic properties of the tight junction barrierChristopher R. WeberRegulation of the tight junction and barrier function85. Regulation of tight junctions in human normal pancreatic duct epithelial cells and cancer cellsTakashi Kojima and Norimasa Sawada93. The role for protein tyrosine phosphatase nonreceptor type 2 in regulating autophagosome formationMichael Scharl and Gerhard Rogler103. Caveolin binds independently to claudin-2 and occludingChristina M. Van Itallie and James M. Anderson108. Regulation of epithelial barrier function by the inflammatory bowel disease candidate gene, PTPN2Declan F. McCole115. Intracellular mediators of JAM-A-dependent epithelial barrier functionAna C. Monteiro and Charles A. Parkos125. Cingulin, paracingulin, and PLEKHA7: signaling and cytoskeletal adaptors at the apical junctional complexSandra Citi, Pamela Pulimeno, and Serge Paschoud133. ZO-2, a tight junction scaffold protein involved in the regulation of cell proliferation and apoptosisLorenza Gonzalez-Mariscal, Pablo Bautista, Susana Lechuga, and Miguel Quiros142. From TER to trans- and paracellular resistance: lessons from impedance spectroscopyDorothee Günzel, Silke S. Zakrzewski, Thomas Schmid, Maria Pangalos, John Wiedenhoeft, Corinna Blasse, Christopher Ozboda, and Susanne M. KrugTight junctions in skin, lung, endothelia, and nervous tissues152. Diverse type of junctions containing tight junction proteins in stratified mammalian epitheliaWerner W. Franke and Ulrich-Frank Pape158. Barriers and more: functions of tight junction proteins in the skinNina Kirschner and Johanna M. Brandner167. Roles for claudins in alveolar epithelial barrier functionChristian E. Overgaard, Leslie A. Mitchell, and Michael Koval175. Claudins and alveolar epithelial barrier function in the lungJames A. Frank184. Relevance of endothelial junctions in leukocyte extravasation and vascular permeabilityDietmar Vestweber193. Involvement of claudins in zebrafish brain ventricle morphogenesisJingjing Zhang, Martin Liss, Hartwig Wolburg, Ingolf E. Blasig, and Salim Abdelilah-Seyfried199. Modulation of tight junction proteins in the perineurium for regional pain controlD. Hackel, A. Brack, M. Fromm, and K. L. Rittner