Christine Gleason, M.D. is an academic neonatologist and Professor Emeritus of Pediatrics at University of Washington and Seattle Children's Hospital. She recently retired from clinical practice and now devotes her time and effort to professional society leadership (Secretary-Treasurer of the American Pediatric Society; member of the Pediatric Policy Council); educational scholarship (Co-Editor of Avery's Diseases of the Newborn); Board certification (Medical Editor at the American Board of Pediatrics); and advisory/consulting activities (FDA Pediatric Advisory Committee; Data Safety & Monitoring Committee of the NIH's Maternal-Fetal Medicine Clinical Trials Network).

• PART I: Overview1. Neonatal and Perinatal Epidemiology2. Ethics, Data, and Policy in Newborn Intensive CarePART II: Fetal Growth and Development3. Development, Function, and Pathology of the Placenta4. Abnormalities of Fetal Growth5. Multiple Gestations and Assisted Reproductive Technology6. Prematurity and Stillbirth: Causes and Prevention7. Nonimmune HydropsPART III: Maternal Conditions Affecting Pregnancy Outcomes8. Maternal Diabetes9. Maternal Medical Disorders of Fetal Significance10. Hypertensive Complications of Pregnancy11. Intrauterine Drug Exposure: Fetal and Postnatal EffectsPART IV: Labor and Delivery12. Assessment of Fetal Well-Being13. Complicated Deliveries14. Obstetric Analgesia and Anesthesia15. Perinatal Transition and Newborn ResuscitationPART V: Essentials of Newborn Care16. Care of the Newborn17. Temperature Regulation18. Newborn ScreeningPART VI: High-Risk Newborn Care19. Neonatal Transport20. Fluid, Electrolyte, and Acid-Base Balance21. Neonatal Pharmacology22. Neonatal Pain and Stress23. Palliative Care24. Risk Assessment and Neurodevelopmental OutcomesPART VII: Genetics25. The Human Genome and Neonatal Care26. Prenatal Diagnosis and Counseling27. The Dysmorphic Infant28. Chromosome DisordersPART VIII: Metabolic Disorders of the Newborn29. Inborn Errors of Carbohydrate, Ammonia, Amino Acid, and Organic Acid Metabolism30. Lysosomal Storage Disorders Presenting in the Neonate31. Congenital Disorders of Glycosylation, Peroxisomal Disorders, and Smith-Lemli-Opitz SyndromePART IX: Immunology and Infections32. Immunology of the Fetus and Newborn33. Neonatal Bacterial Sepsis and Meningitis34. Viral Infections of the Fetus and Newborn35. Congenital Toxoplasmosis, Syphilis, Malaria, and Tuberculosis36. Fungal Infections in the Neonatal Intensive Care Unit37. Healthcare-Associated InfectionsPART X: Respiratory System38. Lung Development39. Neonatal Pulmonary Physiology40. Neonatal Respiratory Therapy41. Control of Breathing42. Acute Neonatal Respiratory Disorders43. Chronic Neonatal Respiratory Disorders44. Anatomic Disorders of the Chest and AirwaysPART XI: Cardiovascular System45. Developmental Biology of the Heart46. Cardiovascular Compromise in the Newborn Infant47. Persistent Pulmonary Hypertension48. Patent Ductus Arteriosus in the Preterm Infant49. Perinatal Arrhythmias50. Congenital Heart Disease51. Long-Term Neurologic Outcomes in Children With Congenital Heart DiseasePART XII: Neurologic System52. Central Nervous System Development53. Congenital Malformations of the Central Nervous System54. Brain Injury in the Preterm Infant55. Neonatal Encephalopathy56. Neonatal Neurovascular Disorders57. Neonatal Neuromuscular Disorders58. Neonatal SeizuresPART XIII: Gastrointestinal System and Nutrition59. Enteral Nutrition60. Parenteral Nutrition for the High-Risk Neonate61. Structural Anomalies of the Gastrointestinal Tract62. Abdominal Wall Defects63. Neonatal Gastroesophageal Reflux64. Necrotizing Enterocolitis and Short Bowel Syndrome65. Disorders of the LiverPART XIV: Hematologic System and Disorders of Bilirubin Metabolism66. Developmental Hematology67. Neonatal Bleeding and Thrombotic Disorders68. Neonatal Platelet Disorders69. Neonatal Erythrocyte Disorders70. Neonatal Transfusion71. Neonatal Leukocyte Physiology and Disorders72. Neonatal Hyperbilirubinemia and KernicterusPART XV: Neoplasia73. Congenital Malignant DisordersPART XVI: Renal and Genitourinary System74. Renal Development75. Developmental Abnormalities of the Kidneys76. Developmental Abnormalities of the Genitourinary System77. Acute Kidney Injury78. Chronic Kidney Disease79. Glomerulonephropathies and Disorders of Tubular Function80. Urinary Tract Infections and Vesicoureteral Reflux81. Systemic HypertensionPART XVII: Endocrine Disorders82. Developmental Endocrinology83. Disorders of Calcium and Phosphorus Metabolism84. Disorders of the Adrenal Gland85. Differences in Sex Development86. Disorders of the Thyroid Gland87. Neonatal Hypoglycemia and HyperglycemiaPART XVIII: Craniofacial and Orthopedic Conditions88. Craniofacial Conditions89. Common Neonatal Orthopedic Conditions90. Skeletal Dysplasias and Heritable Connective Tissue DisordersPART XIX: Dermatologic Conditions91. Newborn Skin Development: Structure and Function92. Congenital and Hereditary Disorders of the Skin93. Infections of the Skin94. Common Newborn Dermatoses95. Vascular Anomalies and Other Cutaneous Congenital DefectsPART XX: Eyes and Ears96. Eye and Vision Disorders97. Ear and Hearing Disorders

"This book is a comprehensive text covering neonatal physiology and the pathophysiology of neonatal disorders. The paper copy is accompanied by an ebook, which is similar in content, with the addition of several videos and links to references. This 11th edition is an update to the previous version, which was published in 2018." -©Doody’s Review Service, 2023, Maradith L Skalak, MD (Tulane University School of Medicine) Doody's Score: 5 Stars!

Christine Gleason, M.D. is an academic neonatologist and Professor Emeritus of Pediatrics at University of Washington and Seattle Children's Hospital. She recently retired from clinical practice and now devotes her time and effort to professional society leadership (Secretary-Treasurer of the American Pediatric Society; member of the Pediatric Policy Council); educational scholarship (Co-Editor of Avery's Diseases of the Newborn); Board certification (Medical Editor at the American Board of Pediatrics); and advisory/consulting activities (FDA Pediatric Advisory Committee; Data Safety & Monitoring Committee of the NIH's Maternal-Fetal Medicine Clinical Trials Network).

• PART I: Overview1. Neonatal and Perinatal Epidemiology2. Ethics, Data, and Policy in Newborn Intensive CarePART II: Fetal Growth and Development3. Development, Function, and Pathology of the Placenta4. Abnormalities of Fetal Growth5. Multiple Gestations and Assisted Reproductive Technology6. Prematurity and Stillbirth: Causes and Prevention7. Nonimmune HydropsPART III: Maternal Conditions Affecting Pregnancy Outcomes8. Maternal Diabetes9. Maternal Medical Disorders of Fetal Significance10. Hypertensive Complications of Pregnancy11. Intrauterine Drug Exposure: Fetal and Postnatal EffectsPART IV: Labor and Delivery12. Assessment of Fetal Well-Being13. Complicated Deliveries14. Obstetric Analgesia and Anesthesia15. Perinatal Transition and Newborn ResuscitationPART V: Essentials of Newborn Care16. Care of the Newborn17. Temperature Regulation18. Newborn ScreeningPART VI: High-Risk Newborn Care19. Neonatal Transport20. Fluid, Electrolyte, and Acid-Base Balance21. Neonatal Pharmacology22. Neonatal Pain and Stress23. Palliative Care24. Risk Assessment and Neurodevelopmental OutcomesPART VII: Genetics25. The Human Genome and Neonatal Care26. Prenatal Diagnosis and Counseling27. The Dysmorphic Infant28. Chromosome DisordersPART VIII: Metabolic Disorders of the Newborn29. Inborn Errors of Carbohydrate, Ammonia, Amino Acid, and Organic Acid Metabolism30. Lysosomal Storage Disorders Presenting in the Neonate31. Congenital Disorders of Glycosylation, Peroxisomal Disorders, and Smith-Lemli-Opitz SyndromePART IX: Immunology and Infections32. Immunology of the Fetus and Newborn33. Neonatal Bacterial Sepsis and Meningitis34. Viral Infections of the Fetus and Newborn35. Congenital Toxoplasmosis, Syphilis, Malaria, and Tuberculosis36. Fungal Infections in the Neonatal Intensive Care Unit37. Healthcare-Associated InfectionsPART X: Respiratory System38. Lung Development39. Neonatal Pulmonary Physiology40. Neonatal Respiratory Therapy41. Control of Breathing42. Acute Neonatal Respiratory Disorders43. Chronic Neonatal Respiratory Disorders44. Anatomic Disorders of the Chest and AirwaysPART XI: Cardiovascular System45. Developmental Biology of the Heart46. Cardiovascular Compromise in the Newborn Infant47. Persistent Pulmonary Hypertension48. Patent Ductus Arteriosus in the Preterm Infant49. Perinatal Arrhythmias50. Congenital Heart Disease51. Long-Term Neurologic Outcomes in Children With Congenital Heart DiseasePART XII: Neurologic System52. Central Nervous System Development53. Congenital Malformations of the Central Nervous System54. Brain Injury in the Preterm Infant55. Neonatal Encephalopathy56. Neonatal Neurovascular Disorders57. Neonatal Neuromuscular Disorders58. Neonatal SeizuresPART XIII: Gastrointestinal System and Nutrition59. Enteral Nutrition60. Parenteral Nutrition for the High-Risk Neonate61. Structural Anomalies of the Gastrointestinal Tract62. Abdominal Wall Defects63. Neonatal Gastroesophageal Reflux64. Necrotizing Enterocolitis and Short Bowel Syndrome65. Disorders of the LiverPART XIV: Hematologic System and Disorders of Bilirubin Metabolism66. Developmental Hematology67. Neonatal Bleeding and Thrombotic Disorders68. Neonatal Platelet Disorders69. Neonatal Erythrocyte Disorders70. Neonatal Transfusion71. Neonatal Leukocyte Physiology and Disorders72. Neonatal Hyperbilirubinemia and KernicterusPART XV: Neoplasia73. Congenital Malignant DisordersPART XVI: Renal and Genitourinary System74. Renal Development75. Developmental Abnormalities of the Kidneys76. Developmental Abnormalities of the Genitourinary System77. Acute Kidney Injury78. Chronic Kidney Disease79. Glomerulonephropathies and Disorders of Tubular Function80. Urinary Tract Infections and Vesicoureteral Reflux81. Systemic HypertensionPART XVII: Endocrine Disorders82. Developmental Endocrinology83. Disorders of Calcium and Phosphorus Metabolism84. Disorders of the Adrenal Gland85. Differences in Sex Development86. Disorders of the Thyroid Gland87. Neonatal Hypoglycemia and HyperglycemiaPART XVIII: Craniofacial and Orthopedic Conditions88. Craniofacial Conditions89. Common Neonatal Orthopedic Conditions90. Skeletal Dysplasias and Heritable Connective Tissue DisordersPART XIX: Dermatologic Conditions91. Newborn Skin Development: Structure and Function92. Congenital and Hereditary Disorders of the Skin93. Infections of the Skin94. Common Newborn Dermatoses95. Vascular Anomalies and Other Cutaneous Congenital DefectsPART XX: Eyes and Ears96. Eye and Vision Disorders97. Ear and Hearing Disorders

"This book is a comprehensive text covering neonatal physiology and the pathophysiology of neonatal disorders. The paper copy is accompanied by an ebook, which is similar in content, with the addition of several videos and links to references. This 11th edition is an update to the previous version, which was published in 2018." -©Doody’s Review Service, 2023, Maradith L Skalak, MD (Tulane University School of Medicine) Doody's Score: 5 Stars!

Christine Gleason, M.D. is an academic neonatologist and Professor Emeritus of Pediatrics at University of Washington and Seattle Children's Hospital. She recently retired from clinical practice and now devotes her time and effort to professional society leadership (Secretary-Treasurer of the American Pediatric Society; member of the Pediatric Policy Council); educational scholarship (Co-Editor of Avery's Diseases of the Newborn); Board certification (Medical Editor at the American Board of Pediatrics); and advisory/consulting activities (FDA Pediatric Advisory Committee; Data Safety & Monitoring Committee of the NIH's Maternal-Fetal Medicine Clinical Trials Network).

• PART I: Overview1. Neonatal and Perinatal Epidemiology2. Ethics, Data, and Policy in Newborn Intensive CarePART II: Fetal Growth and Development3. Development, Function, and Pathology of the Placenta4. Abnormalities of Fetal Growth5. Multiple Gestations and Assisted Reproductive Technology6. Prematurity and Stillbirth: Causes and Prevention7. Nonimmune HydropsPART III: Maternal Conditions Affecting Pregnancy Outcomes8. Maternal Diabetes9. Maternal Medical Disorders of Fetal Significance10. Hypertensive Complications of Pregnancy11. Intrauterine Drug Exposure: Fetal and Postnatal EffectsPART IV: Labor and Delivery12. Assessment of Fetal Well-Being13. Complicated Deliveries14. Obstetric Analgesia and Anesthesia15. Perinatal Transition and Newborn ResuscitationPART V: Essentials of Newborn Care16. Care of the Newborn17. Temperature Regulation18. Newborn ScreeningPART VI: High-Risk Newborn Care19. Neonatal Transport20. Fluid, Electrolyte, and Acid-Base Balance21. Neonatal Pharmacology22. Neonatal Pain and Stress23. Palliative Care24. Risk Assessment and Neurodevelopmental OutcomesPART VII: Genetics25. The Human Genome and Neonatal Care26. Prenatal Diagnosis and Counseling27. The Dysmorphic Infant28. Chromosome DisordersPART VIII: Metabolic Disorders of the Newborn29. Inborn Errors of Carbohydrate, Ammonia, Amino Acid, and Organic Acid Metabolism30. Lysosomal Storage Disorders Presenting in the Neonate31. Congenital Disorders of Glycosylation, Peroxisomal Disorders, and Smith-Lemli-Opitz SyndromePART IX: Immunology and Infections32. Immunology of the Fetus and Newborn33. Neonatal Bacterial Sepsis and Meningitis34. Viral Infections of the Fetus and Newborn35. Congenital Toxoplasmosis, Syphilis, Malaria, and Tuberculosis36. Fungal Infections in the Neonatal Intensive Care Unit37. Healthcare-Associated InfectionsPART X: Respiratory System38. Lung Development39. Neonatal Pulmonary Physiology40. Neonatal Respiratory Therapy41. Control of Breathing42. Acute Neonatal Respiratory Disorders43. Chronic Neonatal Respiratory Disorders44. Anatomic Disorders of the Chest and AirwaysPART XI: Cardiovascular System45. Developmental Biology of the Heart46. Cardiovascular Compromise in the Newborn Infant47. Persistent Pulmonary Hypertension48. Patent Ductus Arteriosus in the Preterm Infant49. Perinatal Arrhythmias50. Congenital Heart Disease51. Long-Term Neurologic Outcomes in Children With Congenital Heart DiseasePART XII: Neurologic System52. Central Nervous System Development53. Congenital Malformations of the Central Nervous System54. Brain Injury in the Preterm Infant55. Neonatal Encephalopathy56. Neonatal Neurovascular Disorders57. Neonatal Neuromuscular Disorders58. Neonatal SeizuresPART XIII: Gastrointestinal System and Nutrition59. Enteral Nutrition60. Parenteral Nutrition for the High-Risk Neonate61. Structural Anomalies of the Gastrointestinal Tract62. Abdominal Wall Defects63. Neonatal Gastroesophageal Reflux64. Necrotizing Enterocolitis and Short Bowel Syndrome65. Disorders of the LiverPART XIV: Hematologic System and Disorders of Bilirubin Metabolism66. Developmental Hematology67. Neonatal Bleeding and Thrombotic Disorders68. Neonatal Platelet Disorders69. Neonatal Erythrocyte Disorders70. Neonatal Transfusion71. Neonatal Leukocyte Physiology and Disorders72. Neonatal Hyperbilirubinemia and KernicterusPART XV: Neoplasia73. Congenital Malignant DisordersPART XVI: Renal and Genitourinary System74. Renal Development75. Developmental Abnormalities of the Kidneys76. Developmental Abnormalities of the Genitourinary System77. Acute Kidney Injury78. Chronic Kidney Disease79. Glomerulonephropathies and Disorders of Tubular Function80. Urinary Tract Infections and Vesicoureteral Reflux81. Systemic HypertensionPART XVII: Endocrine Disorders82. Developmental Endocrinology83. Disorders of Calcium and Phosphorus Metabolism84. Disorders of the Adrenal Gland85. Differences in Sex Development86. Disorders of the Thyroid Gland87. Neonatal Hypoglycemia and HyperglycemiaPART XVIII: Craniofacial and Orthopedic Conditions88. Craniofacial Conditions89. Common Neonatal Orthopedic Conditions90. Skeletal Dysplasias and Heritable Connective Tissue DisordersPART XIX: Dermatologic Conditions91. Newborn Skin Development: Structure and Function92. Congenital and Hereditary Disorders of the Skin93. Infections of the Skin94. Common Newborn Dermatoses95. Vascular Anomalies and Other Cutaneous Congenital DefectsPART XX: Eyes and Ears96. Eye and Vision Disorders97. Ear and Hearing Disorders

"This book is a comprehensive text covering neonatal physiology and the pathophysiology of neonatal disorders. The paper copy is accompanied by an ebook, which is similar in content, with the addition of several videos and links to references. This 11th edition is an update to the previous version, which was published in 2018." -©Doody’s Review Service, 2023, Maradith L Skalak, MD (Tulane University School of Medicine) Doody's Score: 5 Stars!