Autonomic Dysfunction in Parkinson's Disease

Cristian Falup-Pecurariu is Head of the Department of Neurology, County Clinic Hospital from Brasov, and is Full Professor of Neurology at the Transilvania University from Brasov, Romania. He received his medical degree from the University of Medicine and Pharmacy “Iuliu Hatieganu” from Cluj-Napoca. He hold a 1 year fellowship of the European Neurological Society in movement disorders at Hospital Clinic, University of Barcelona, Spain.During his career Cristian Falup-Pecurariu was President of the European Association of Young Neurologists and Trainees (EAYNT), EAYNT Liasion Officer with World Federation of Neurological Society, co-representative of Europe on the International Working Group for Young Neurologists and Trainees (World Federation of Neurology). He was also Secretary of the EFNS/MDS-ES Panel on Movement Disorders, member of the Educational Committee of MDS-ES, member of the MDS Leadership Task Force and European Academy of Neurology Scientific Panel Movement Disorders, member of the Teaching Course sub-Committee of the European Academy of Neurology (EAN), currently being member of the Program Committee of EAN. Falup-Pecurariu is former Chair of the Education Committee of the MDS-ES, former member of the Executive Committee of MDS-ES, former member of the International Executive Committee of MDS. He is the initiator and Course Director of the Movement Disorders Teaching Course held in Brasov (12th editions). His research focuses on motor and non-motor aspects of Parkinson’s diseases.Professor Peter Jenner is a specialist in preclinical aspects of neurodegenerative diseases, notably Parkinson’s disease. He has spent the major part of his career at King’s College London where he was Head of Pharmacology for 14 years before returning to his research roots and subsequently becoming Emeritus Professor of Pharmacology. Peter has expertise in drug metabolism and pharmacokinetics but neuropharmacology based on functional models of neurodegenerative diseases has formed the major focus of his work. Peter holds a BPharm, PhD and DSc degree from the University of London. He has published well over 1000 articles with more than 700 peer reviewed papers. He is a Fellow of the Royal Pharmaceutical Society, the British Pharmacological Society, the Royal Society of Medicine and of King’s College London. Peter was recently honoured with a Doctor Honoris Causa degree from Carol Davila University of Medicine and Pharmacy, Bucharest and made an Honorary Fellow of The British Pharmacological Society for his contribution to research in to movement disorders.Peter has worked closely with the pharmaceutical industry for many years and acts as an adviser and consultant to both major pharma and biotech companies. He has a wide knowledge of the drug discovery and drug development process and has been involved from molecule synthesis through to drug registration for use in man. Peter was the Founder, Director and Chief Scientific Officer of Proximagen, a biotech focussed on the treatment and cure of neurodegenerative diseases that was listed on AIMs and subsequently purchased by a US based healthcare company. He is a regular speaker at international meetings and also takes time to speak at Parkinson’s disease patient-carer groups across the UK.

• PrefaceCristian Falup-Pecurariu1. Autonomic nervous system-Anatomy, physiology, and biochemistryIva Stanković, Ivan Adamec, Vladimir Kostić and Mario Habek2. General approach to patients with autonomic dysfunction in Parkinson’s diseaseValentina Leta, Vanessa Raeder and K Ray Chaudhuri3. Rating scales for dysautonomia in Parkinson’s diseaseȘtefania Diaconu, Laura Irincu, Irina Ivan and Cristian Falup-Pecurariu4. Assessing autonomic dysfunction with functional imaging in Parkinson's diseaseJacob Horsager,Casper Skjærbæk and Per Borghammer5. Cardiovascular autonomic failure in Parkinson's diseaseFabian Leys, Gregor K. Wenning and Alessandra Fanciulli6. Drooling and dysphagia in Parkinson's diseaseMauricio Paez Maggio, Santiago Perez Lloret and Marcelo Merello7. Gastrointestinal dysfunction in Parkinson's diseaseJonathan Timpka and Per Odin8. Urinary dysfunction in Parkinson's diseaseRoongroj Bhidayasiri,Warongporn Phuenpathom and Yoshio Tsuboi9. Autonomic dysfunction during sleep in Parkinson's diseaseFrancesca Baschieri, Pietro Guaraldi, Pietro Cortelli and Giovanna Calandra-Buonaura10. Thermoregulatory dysfunctions in idiopathic Parkinson’s diseaseBrim, Bianca and Struhal, Walter