Autoantibodies

Inbunden, Engelska, 2013

Av Yehuda Shoenfeld, Pier Luigi Meroni, M. Eric Gershwin, Israel) Shoenfeld, Yehuda (Zabludowitcz Center of Autoimmunity, Sheba Medical Center and Reichman University, Herzelya, Italy) Meroni, Pier Luigi (Department of Clinical Sciences & Community Health, University of Milan, CA) Gershwin, M. Eric, MD (Division of Rheumatology, Allergy & Clinical Immunology, University of California at Davis School of Medicine, Davis, M Eric Gershwin

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Autoimmune diseases are characterized by the occurrence of antibodies reacting with self-constituents of the body. The fully updated third edition of Autoantibodies is an in-depth review of the main autoantibodies identified up to now, with particular emphasis on those that display a diagnostic or prognostic clinical value.

The new edition covers recent scientific advances, diagnostic techniques, and therapeutic technologies. Each chapter is focused on a single family of autoantibodies. This important reference contains historical notes, definitions, origins and sources of antigens recognized genetic associations, mediated pathogenic mechanisms, methods of detection, as well as clinical utility (disease prevalence and association, diagnostic value, sensitivity and specificity, prognostic value). This is an ideal reference for anyone involved in the field of autoimmune diseases.

Presents all known, important autoantibodies in a single source, focusing on the antibodies needed for autoimmune disorder diagnosis
Includes clinical applications for each autoantibody along with general information
Organized by disease and disorder type, by autoantibody family, and completely cross-referenced

Produktinformation

Utgivningsdatum2013-12-10
Mått191 x 235 x 55 mm
Vikt1 980 g
FormatInbunden
SpråkEngelska
Antal sidor916
Upplaga3
FörlagElsevier Science
ISBN9780444563781

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Onkologi inom Medicin

Professor Yehuda Shoenfeld is the President of the Center for Autoimmune Diseases (present), incumbent of the Laura Schwarz-Kipp Chair for Research of Autoimmune Diseases in Tel Aviv University (since 2002–Present), Emeritus Professor of the Sackler School of Medicine in Tel Aviv University and teaches medical studies and MSc and PhD students (since 1985). Prof. Shoenfeld has edited a series of textbooks entailing "The Mosaic of Autoimmunity," "Autoantibodies," "Infection and Autoimmunity," and "Diagnostic Criteria of Autoimmune Diseases" (Elsevier Pub.). He has served on 36 editorial boards and is the organizer of more than 25 international congresses on autoimmunity. He is the author of > 2000 peer-reviewed papers reported in the field of autoimmunity and internal medicine. More than 65,000 citations.

FOREWORD: THE CONCEPT OF IMMUNODIAGNOSISINTRODUCTION: AUTOANTIBODIES-UNIQUE CHARACTERISTICSALLERGIC DISEASE AUTOANTIBODIESANTINEUTROPHIL ANTIBODIESINTRODUCTION: ANTINUCLEAR ANTIBODIESAUTOANTIBODIES TO BIOLOGIC FACTORS/STRUCTURESCARDIAC AUTOANTIBODIESENDOCRINE AUTOANTIBODIESGI AND LIVER AUTOANTIBODIESHEMATOLOGIC AUTOANTIBODIESKIDNEY AUTOANTIBODIESNEUROLOGICAL SYSTEM AUTOANTIBODIESRHEUMATIC DISEASE AUTOANTIBODIESSKIN DISEASE AUTOANTIBODIESUNIQUE CLINICAL SITUATIONS

"...a comprehensive reference covering the most important known autoantibodies, with particular emphasis on those that display a clinical value...fully updated to include recent scientific advances, diagnostic techniques and therapeutic technologies." --Anticancer Research, February 2015"This is an extraordinary, comprehensive, seminal book that is also easy to read. The extensive research of the last few years has advanced the science in dramatic ways and this book has a unique and unmatched presentation of the current understanding of autoantibodies, and their impact on health and disease and begins the discussion of the available treatment options and possibilities for future research." --Doody.com, July 18, 2014 "Almost completely revised and updated…in relation to recent advances in the field, this is the third edition of a textbook describing clinical and research aspects of autoantibodies. Some 150 specific autoantibodies are reviewed, both in terms of their clinical significance to the practicing physician and in relation to research interest in immunoglobulin self-reactivity against tissue antigens." --ProtoView.com, April 2014