• Foreword.–  Introduction.– Mitral Valve Anatomy and Current Surgical and Percutaneous Approaches to Mitral Regurgitation.– Device description and procedural overview. – Room Set-up.– Summary of MitraClip Clinical Data and Approach to Patient Selection. –Echocardiographic Evaluation of Patients Before and After MitraClip Mitral Valve Repair.– MitraClip Procedural Echocardiography.– Transseptal puncture.– Venous Access Management.- Hemodynamic perspectives of edge-to-edge mitral valve repair.- Situational Steering Techniques.- Case example: EVEREST II: Basic Degenerative.– Case example: EVEREST II: Basic Functional.– Case example: Barlow’s disease.- Case example: EVEREST II : Large left atrium.- Case example: Approach to Mitral Regurgitation requiring multiple MitraClips.- Case example: Two Clips.– Case example: EVEREST II: Delayed second clip for early recurrent mitral regurgitation.– Case example: Secondary mitral regurgitation due to ischaemic mitral valve disease and mild rheumatic mitral valve involvement.– Case example: The dilemma of reducing functional mitral regurgitation versus development of mitral stenosis.– Case example: Infective endocarditis associated with the Mitraclip.- Case example: EVEREST II: MitraClip after failed surgical mitral valve repair.– Case example: EVEREST II: Functional Mitral Regurgitation.– Case example: Chiari Network Complicating a MitraClip Procedure.– Case example: EVEREST II: Two MitraClip Procedure with Partial Detachment of Second Device.- Case example: Mitraclip Procedure in Unusual Heart Position.- Interatrial Septal Tear: A rare complication during MitraClip procedure and successful transcatheter closure.– Case example: Percutaneous double-valve treatment in a patient with degenerative aortic stenosis and functional mitral regurgitation.- Case example: Percutaneous mitral valve repair after previous mitral valve reconstruction.- Case example: Delayed functional MitralRegurgitation in high risk patients and Complex degenerative mitral regurgitation (anterior leaflet prolapsed) with commissural impingement.- Case example: Severe functional mitral regurgitation with missing leaflet coaptation.- Case example: Severe Ischemic Heart Failure with Functional Improvement After MitraClip Therapy.- Case example: Severe left-to-right shunting from iatrogenic atrial septal defect.- Case example: MitraClip implantation in chronic degenerative mitral regurgitation with extensive calcification.- Case example: 3D Transesophageal Echo Guided MitraClip Treatment of P3 Mitral Valve Prolapse.- Case example: Failure and complications of a MitraClip implantation for severe functional mitral regurgitation: a combination of unexpected findings and early experience.- Case example: Mitral valve repair using the MitraClip system in a patient with severe mitral regurgitation in the A3/P3 region due to chordae rupture during transapical TAVI.- Case example: MitraClip implantation in a patient with severe mitral annulus calcifications and a small orifice area.– Case example: Functional Mitral Regurgitation treatment with Mitraclip: Difficult transseptal puncture with anterior approach complicated by right atrial thrombus.- Case example: MitraClip in a patient with dextrocardia and scoliosis complicated by delayed clip detachment.– Case example: Massive air embolism during MitraClip insertion.- Case example: The degree and type of mitral regurgitation present at the baseline is not always a good predictor of the procedural technical needs and of the final result.- Case example: Functional mitral regurgitation with a wide extension of the central regurgitant jet.- Case example: Percutaneous edge-to-edge mitral valve repair for functional mitral regurgitation in a high surgical risk patient.- Case example: Mitral stenosis after MitraClip therapy and a partial solution for treatment.- Case Example: MitraClip Therapy for Functional Mitral Regurgitation:Importance of jet localization to direct MitraClip placement.- Case Example: MitraClip: Acute thrombus formation during guide insertion.- MitraClip Placement in a Patient with Severe Kyphoscoliosis and Bileaflet Prolapse.

From the book reviews: Selected as "Highly Commended" at BMA Medical Book Awards for 2014. "The style of writing is clear to understand, even for those with relatively little specific prior expertise in the field. This book will be very helpful as a source of reference for all those who will be involved in the procedure. ... The book fills a gap in the market as no equivalent book exists to my knowledge, collating all this relevant data, expert advice and case examples in one place." (BMA Medical Book Awards, September, 2014)