Asymmetric Organocatalysis

Albrecht Berkessel is full professor at the university of Cologne, Germany. His research interests are catalysis, combinatorial chemistry and solid phase chemistry.Harald Groger is currently working at the Degussa AG. His research is focussed on enzymatic reactions and biocatalysis.

• IntroductionGeneral Mechanistic ConsiderationsNucleophilic Substitution at Aliphatic CarbonNucleophilic Addition to Electron-deficient C=C Double BondsNucleophilic Addition to C=N Double BondsNucleophilic Addition to C=O Double BondsNucleophilic Addition to Unsaturated NitrogenCycloaddition ReactionsProtonation of Enolates and Tautomerization of EnolsOxidationReduction of Carbonyl CompoundsKinetic Resolution of Racemic Alcohols and AminesDesymmetrization and Kinetic Resolution of AnhydridesLarge-Scale ApplicationsAppendix: Tabular Survey of Organo-Catalysts, Synthesis and Application

"This fascinating monograph captures the diversity and power of an area of research whose roots extend deep within the organic chemistry literature, yet which has only recently achieved critical mass through the collective contributions of many present-day pioneers. ... is an essential addition to both academic and industrial research libraries, as well as to the personal collection of any scientist with an interest in catalysis or synthetic chemistry." Angewandte Chemie I.E. "... well-written with clear, focused schemes... of great value to those involved in synthetic methodology, catalysis, and total synthesis." Journal of the American Chemical Society "On the whole, the authors succeeded in covering a very broad range of reactions that are catalyzed by organic catalysts, and offer readers an excellent overview of the current situation in the field of asymmetric organocatalysis. This book can be recommended for all scientists working in the area of asymmetric catalysis, whether in industrial research and development or at the universities. Postgraduate students and postdoctoral researchers who have begun work on this rapidly growing field would derive considerable benefit from reading it."Synthesis "This monograph will be a valuable addition into personal collections of synthetic chemists and research libraries of academia and industry." E-STREAMS