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Prashant Kesharwani - Aptamers Engineered Nanocarriers for Cancer Therapy, Häftad

Häftad, Engelska, 2022

Del i serien Woodhead Publishing Series in Biomaterials

Aptamers Engineered Nanocarriers for Cancer Therapy

Av Prashant Kesharwani

3419 kr

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Beskrivning

Aptamers Engineered Nanocarriers for Cancer Therapy details the selection technologies, biological characteristics, and clinical uses of aptamer-based nano agents for cancer therapeutics. The book helps facilitate speedy solutions for some of the problems pertaining to the manufacture of nano-aptamers - such as toxicity, thermal stability, cost efficiency, tumor penetration and blood stability. Key chapters cover cell-SELEX technology for aptamer selection, mechanisms of multi-drug resistance of cancer, the relevance of aptamers as anticancer therapies, as well as the broad range of aptamer-functionalized nanostructures available.

This book provides exciting insights into this relatively new approach to cancer therapeutics, and will be of interest to materials scientists, biomedical engineers, molecular biologists, biochemists and clinical scientists, with a focus on cancer therapy.



  • Reviews the mechanisms behind multi-drug resistance (MDR) in cancer and how aptamer-mediated novel therapeutic agents and strategies can facilitate MDR reversal
  • Covers a range of aptamers engineered nanostructures, including PLGA nanoparticles, silica nanoparticles, quantum dots, nucleic acid aptamers, and more
  • Discusses the challenges associated with using aptamers as cancer therapeutics and how this translates into clinical use
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Dr. Prashant Kesharwani, PhD, is an Assistant Professor of Pharmaceutics at Department of Pharmaceutical Sciences, Dr.Harisingh Gour Vishwavidyalaya University, Sagar, Madhya Pradesh, India. He has more than 12 years of teaching, research,and industrial experience across various countries. An overarching goal of his current research is the development ofnanoengineered drug delivery systems for various diseases. He has more than 400 international publications in well-reputedjournals and more than 30 international books (Elsevier). His work has garnered 40,000 + citations, with an h-index of above100, making him one of the youngest Indian researchers to achieve an h-index of 100 at the age of 41. He is a recipientof many research grants from various funding bodies. He is also the recipient of several internationally acclaimed awards,such as “USERN Laureate award” and “SERB-Ramanujan Fellowship Award.” He has presented many invited talks and oralpresentations at prestigious scientific peer-conferences, received international acclaims and awards for research contribution,supervised students/junior researchers, and actively participated in outreach and scientific dissemination for the service ofthe wider community.

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