Applications of Nanotechnology in Drug Discovery and Delivery

Chukwuebuka Egbuna (PhD) is a chartered chemist and academic researcher. He is a member of the Institute of Chartered Chemists of Nigeria (ICCON), the Nigerian Society of Biochemistry and Molecular Biology (NSBMB), and the Royal Society of Chemistry (RSC) (United Kingdom). Dr. Egbuna is the founder and editor of the Elsevier book series on Drug Discovery Update. The series includes books, monographs, and edited collections from all areas of drug discovery including emerging therapeutic claims for the treatment of diseases. He has published research articles in many international journals of repute and is ranked among the top 500 Nigerian scientists in SciVal/SCOPUS. He has edited more than 25 books with Elsevier, Springer, Wiley, and Taylor & Francis. His most recent book is the three volume Coronavirus Drug Discovery, published by Elsevier. Dr. Egbuna is the founder and the publishing director of IPS Intelligentsia Publishing Services. Mihnea-Alexandru Găman received his MD at the Faculty of Medicine, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania. Dr. Găman is currently specializing in clinical hematology at the Department of Hematology, Centre of Hematology and Bone Marrow Transplantation, Fundeni Clinical Institute, Bucharest, Romania. He has published more than 100 papers in international impact factor journals, as well as served as editor and author for international and national books/book chapters. In addition, Dr. Găman also serves as Scientific Editor, Associate Editor, Editorial Board Member and Peer-Reviewer for several international and national journals. His main fields of interest include hematology, molecular biology, oncology, internal medicine, medical education, fundamental sciences, and translational/interdisciplinary medicine.Dr. Jaison Jeevanandam is a Senior Researcher at the National Institute of Mental Health (NUDZ) in the Czech Republic. He earned his Ph.D. in Chemical Engineering from the Faculty of Engineering and Science at Curtin University, Malaysia. He has extensive experience in nanoparticle synthesis, particularly green synthesis using plant extracts, as well as nanoparticle characterization, cytotoxicity analysis, and in vitro diabetic models. His current research focuses on the application of nanobiotechnology in the development of nanoformulations for drug delivery systems.

• Part 1: Fundamentals of Nanotechnology Application in Drug Discovery1. Nanotechnology: History, Trends and Modern Application2. Nanomaterials as Drug Candidates: Types, Synthesis and Preparatory Methods3. Factors Affecting the Choice for Nanoparticles in Drug Discovery4. Nanoparticle Formulation: Types, Steps and Procedures5. Nanocarriers: Types, Synthesis and Fabrication Methods6. Factors Affecting the Choice for Nanocarriers for Efficient Drug Delivery Applications7. Characterization of Nanoparticles: Methods and TechniquesPart II: Application of Nanotechnology in Drug Discovery and Therapy8. Applications   of Nanotechnology in Pharmaceutical Products9. Applications of Nanotechnology in Target Identification and Validation10. Applications of Nanotechnology in Lead Identification and Optimization11. Application of Nanotechnology in Pharmaceutical Product Delivery12. Application of Nanotechnology in Medicine in the Treatment of DiseasesPart III: Safety Issues and Challenges13. Nanotoxicology: Toxicity of Nanoparticles in Biomedical Application14. In vitro and In vivo Toxicity of Metal Nanoparticles and their Drug Delivery Applications15. Application of Nanoelectromechanical Systems for the Detection of Toxic Chemical Agents in Pharmaceutical Products: Nanobiosensor Application16. Policy Issues, Risk Assessment and Regulations of the Application of Nanotechnology in Drug Discovery