Apolipoprotein E in Health and Disease

Nyhet

Unravelling its Intricate Roles

Häftad, Engelska, 2026

AvDileep Kumar,Ankit Ganeshpurkar,Aditya Ganeshpurkar

2 119 kr

Kommande

Apolipoprotein E in Health and Disease: Unravelling its Intricate Roles delves into the multifaceted functions of Apolipoprotein E (ApoE) across various health conditions and diseases. This comprehensive volume offers an in-depth exploration of ApoE, illuminating its structural insights, functional significance, and genetic variability. Each chapter examines the role of ApoE in different disease contexts, including cardiovascular diseases, Alzheimer's disease, neurological disorders, metabolic syndrome, liver health, cancer, and inflammatory disorders. Key chapters investigate ApoE's impact on lipid metabolism, atherosclerosis, and heart health while also probing its involvement in genetic predispositions and mechanistic implications in Alzheimer's disease.
In addition, the book extends its exploration to the broader influence of ApoE on cognitive decline and other neurological conditions, metabolic health, liver function, cancer risk, and immune modulation. With a strong focus on the pharmacogenetics of ApoE, the book paves the way for precision medicine, offering insights into how ApoE genotypes influence medication responses and therapeutic strategies. Future prospects and challenges in harnessing ApoE for disease management are discussed, alongside its role in infectious diseases, genetic engineering innovations, and targeted drug delivery systems.

Provides a comprehensive examination of Apolipoprotein E (ApoE) in various health conditions and diseases, including cardiovascular diseases, Alzheimer's, neurological disorders, and cancer
Delivers detailed insights into the genetic variability of ApoE, explaining how different genotypes influence disease risk and therapeutic responses
Integrates perspectives from biochemistry, molecular biology, genetics, neurology, and cardiology to offer a holistic understanding of ApoE
Highlights the pharmacogenetics of ApoE, illustrating its potential in personalized medicine and targeted therapeutic strategies

Produktinformation

Utgivningsdatum2026-04-03
Mått191 x 235 x undefined mm
Vikt450 g
FormatHäftad
SpråkEngelska
Antal sidor325
FörlagElsevier Science
ISBN9780443405631

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Biovetenskap inom Naturvetenskap och teknik

Dileep Kumar received his B. Pharm from Manipal College of Pharmaceutical Sciences, Manipal University, and M. Pharm from S.G.S.I.T.S Indore, Madhya Pradesh. He has several patents to his credit. He was awarded a Junior Research fellowship by National Medicinal Plant Board (NMPB) New Delhi, Senior Research Fellowship from University Grants Commission (UGC), Teaching Assistantship, and institute Post-Doctoral fellowship from IIT (BHU) Varanasi. At present, he is teaching as an assistant professor at Poona College of pharmacy, Bharti Vidyapeeth University Pune. He has published many papers and patents. He is Guest editor of several Prestigious journals. At present he is visiting professor in the department of entomology and Comprehensive Cancer Center in university of California Davis Dr. Ganeshpurkar's primary goal is to establish a distinct presence in the realm of medicinal chemistry and drug design research, with a specific focus on harnessing computational tools and artificial intelligence to advance the processes of lead discovery and optimization. His research is centred around in silico drug design, lead identification, and optimization. Additionally, his work encompasses the design, synthesis, and thorough biological assessment of novel leads tailored to address diverse pathophysiological conditions, including but not limited to Alzheimer's disease and various neurodegenerative disorders. Dr. Aditya Ganeshpurkar holds a Ph.D. in pharmacology and has extensive experience in both academics and research. His research primarily focuses on pharmacological and nutraceutical studies, with an emphasis on drug discovery, evaluation, and immunomodulation. Dr. Ganeshpurkar has published numerous research articles, review articles, and book chapters in various scientific journals and has presented his work at national seminars and conferences. His research areas include the evaluation of herbal and synthetic drugs, immunomodulatory potential, and the development of drug delivery systems. He has more than 3000 citations with h index of 28 and holds a place in top 2% of scientist in the pharmacy field.

1. Apolipoprotein E (ApoE): Structural Insights, Functionality, and Genetic Variability2. Apolipoprotein E and Cardiovascular Pathophysiology: A Comprehensive Exploration3. Apolipoprotein E in Alzheimer's Disease: Genetic Predisposition and Mechanistic Implications4. Apolipoprotein E and Neurological Disorders: Beyond Alzheimer's Disease5. Apolipoprotein E's Impact on Metabolic Syndrome: A Systematic Analysis6. Apolipoprotein E and Liver Health: Implications in Lipid Metabolism and Disease7. Apolipoprotein E and its Role in Cancer: Insights into Carcinogenic Associations8. Apolipoprotein E's Immune Mediation: Implications in Inflammatory Disorders9. Pharmacogenetics of Apolipoprotein E: Precision Medicine and Therapeutic Implications10. Challenges and Prospects in Targeting ApoE for Disease Management11. Apolipoprotein E and Infectious Diseases: A Framework for Therapeutic Developments12. Genetic Engineering of Apolipoprotein E: Innovations and Clinical Applications13. Apolipoprotein E and Precision Medicine: Individualized Disease Management Approaches14. Apolipoprotein E in Drug Delivery Systems: Targeted Pharmacotherapeutics15. Apolipoprotein E and Autoimmune Disorders: Therapeutic Frontiers