Del 112 i serien Experientia Supplementum
Antibody Glycosylation
Inbunden, Engelska, 2021
1 989 kr
Beställningsvara. Skickas inom 10-15 vardagar. Fri frakt för medlemmar vid köp för minst 249 kr.
Finns i fler format (1)
This book summarizes recent advances in antibody glycosylation research. Covering major topics relevant for immunoglobulin glycosylation - analytical methods, biosynthesis and regulation, modulation of effector functions - it provides new perspectives for research and development in the field of therapeutic antibodies, biomarkers, vaccinations, and immunotherapy.Glycans attached to both variable and constant regions of antibodies are known to affect the antibody conformation, stability, and effector functions. Although it focuses on immunoglobulin G (IgG), the most explored antibody in this context, and unravels the natural phenomena resulting from the mixture of IgG glycovariants present in the human body, the book also discusses other classes of human immunoglobulins, as well as immunoglobulins produced in other species and production systems. Further, it reviews the glycoanalytical methods applied to antibodies and addresses a range of less commonly explored topics, such as automatization and bioinformatics aspects of high-throughput antibody glycosylation analysis. Lastly, the book highlights application areas ranging from the ones already benefitting from antibody glycoengineering (such as monoclonal antibody production), to those still in the research stages (such as exploration of antibody glycosylation as a clinical or biological age biomarker), and the potential use of antibody glycosylation in the optimization of vaccine production and immunization protocols. Summarizing the current knowledge on the broad topic of antibody glycosylation and its therapeutic and biomarker potential, this book will appeal to a wide biomedical readership in academia and industry alike.Chapter 4 is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.
Produktinformation
- Utgivningsdatum2021-10-23
- Mått155 x 235 x 38 mm
- Vikt1 062 g
- FormatInbunden
- SpråkEngelska
- SerieExperientia Supplementum
- Antal sidor591
- FörlagSpringer Nature Switzerland AG
- ISBN9783030769116
Tillhör följande kategorier
Hoppa över listan
Mer från samma serie
Del 108
Inflammasomes: Clinical and Therapeutic Implications
Mario D. Cordero, Elísabet Alcocer-Gómez
Häftad, 2019
2 209 kr
Del 110
Del 109
Del 111
Del 111
Del 113
Del 113
Del 114
Del 114
Hoppa över listan
Du kanske också är intresserad av
Del 112
- Nyhet
Del 3
- Nyhet
Del 11
- Nyhet
- Nyhet
Del 4
Del 2
Del 1
- Nyhet
Del 6
- Nyhet
Del 4
Del 3