Antibiotics as Anti-Inflammatory and Immunomodulatory Agents

• Basic research.- Effects of antibiotics on Pseudomonas aeruginosa virulence factors and quorum-sensing system.- Antibiotics, inflammation and its resolution: An overview.- The cytoprotective interactions of antibiotics with human ciliated airway epithelium.- Chemotaxis.- Cytokines.- Antibacterial agents and the oxidative burst.- Immune system.- Macrolides and mucus production.- Ion channel regulation.- Clinical results.- The use of macrolides for treatment of diffuse panbronchiolitis.- Macrolides in cystic fibrosis.- Macrolides and upper airway/sinus disease.- Benefits of macrolides in the treatment of asthma.- Roles of macrolides in treatment of lung injury.- Macrolides and cancer, arthritis and IBD.- Anti-inflammatory properties of antibiotics other than macrolides.

This concise and well-illustrated monograph contains much information of value to clinical immunologists and microbiologists engaged in research on the management and treatment of infectious diseases." (Clinical Infectious Diseases)