Anion Channels and Transporters

Inbunden, Engelska, 2024

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Similar anion channels and transporters are expressed in multiple tissues – often fulfilling similar cellular tasks, but also clearly distinct functions.

Produktinformation

Utgivningsdatum2024-01-05
Mått155 x 235 x 25 mm
Vikt790 g
FormatInbunden
SpråkEngelska
SerieHandbook of Experimental Pharmacology
Antal sidor362
FörlagSpringer International Publishing AG
ISBN9783031513459

Tillhör följande kategorier

Farmakologi inom Medicin
Fysiologi inom Medicin

Preface.- Muscle chloride channels.- Adrenal anion channels - new roles in zona glomerulosa physiology and in the pathophysiology of primary aldosteronism.- ClC-K Kidney Chloride Channels : from structure to pathology.- Biophysical and pharmacological insights to CLC chloride channels and Transporters.- Function and regulation of the calcium-activated chloride channel anoctamin 1.- Structure and function of calcium-activated chloride channels and scramblases in TMEM16 family.- Structural basis for anion-selective Cys-loop receptor signal transduction and modulation.- Physiological functions of the volume regulated anion channel VRAC/LRRC8 and the proton-activated chloride channel PAC/TMEM206.- CFTR modulators: from mechanism to targeted therapeutics.- Structure, physiology, and pharmacology of chloride-dependent cation cotransporters.- SLC26 Anion Transporters.- Pharmacology of Na-dependent transporters of inorganic phosphate.- Simulation of fluoride anions in CLC proteins: from potent inhibition to selective transport.