Dr. Bernard Le Foll is a Clinician Scientist specializing in Addiction. He is Chair of Addiction Psychiatry within the Department of Psychiatry of University of Toronto. He is Head of the Translational Addiction Research Laboratory in the Campbell Family Mental Health Research Institute. He is also the Lead, Clinical Research Innovation Service within the Addiction Division at CAMH. He is Head of the Alcohol Research and Treatment Clinic at CAMH. He is Professor at University of Toronto in the departments of Family and Community Medicine, Pharmacology and Toxicology, Psychiatry ,Institute of Medical Sciences and Dalla Lana School of Public Health.

• PART I Introduction to anandamide1 Regulation of the levels of anandamide and its bioactive congeners by biosynthesis and degradationVincenzo Di Marzo and Cristoforo Silvestri2 Imaging the endocannabinoid enzyme fatty acid amide hydrolase in the living human brainClaire Shyu, Shamantha Lora, Laura M. Best, Sheldon Bereznick and Isabelle Boileau3 Anandamide: From modulation of neuronal excitation to antimicrobial activities--What is in common?Ronit Vogt Sionov and Doron SteinbergPART II Anandamide in diseases4 Anandamide and mood disordersJacklynn M. Fitzgerald and Cecilia J. Hillard5 Anandamide and anxietySara Liane Kroll and Leah M. Mayo6 Anandamide and disease. Role in stress, fear, and PTSDLuke J. Ney and Allison Matthews7 Anandamide in disease: Role in psychosisM. Belen Blasco, Carlos A. Pretell Annan and Romina Mizrahi8 Anandamide in personality disordersNathan J. Kolla and Michelle De Pol9 A brief review of anandamide in cannabis use and cannabis use disorderRaesham Mahmood, Claudia Poluga, Isabelle Boileau and Laura M. Best10 Anandamide signaling dysfunction in the development of alcohol use disordersBalapal S. Basavarajappa11 Role of Anandamide in Nicotine AddictionBernard Le Foll12 The role of anandamide in the sleep--wake cycleMonica Mendez Dıaz, Yalitza Azucena Alvarado Ramırez, Aline Ostos Valverde, Oscar E. Prospero Garcıa and Andrea M. Herrera Solıs13 Anandamide in disease: The good and bad in epilepsyRenaud Gom, Pasindu Wickramarachchi, Roberto Colangeli and G. Campbell Teskey14 Role of anandamide in Alzheimer’s diseaseDina Medina-Vera and Simone Tambaro15 The role of anandamide in digestive and defensive functions of the gutKeith A. Sharkey and Derek K.L. Tsang16 The role of anandamide and the endocannabinoids in the treatment and regulation of nausea and vomitingErin M. Rock and Linda A. Parker

Dr. Bernard Le Foll is a Clinician Scientist specializing in Addiction. He is Chair of Addiction Psychiatry within the Department of Psychiatry of University of Toronto. He is Head of the Translational Addiction Research Laboratory in the Campbell Family Mental Health Research Institute. He is also the Lead, Clinical Research Innovation Service within the Addiction Division at CAMH. He is Head of the Alcohol Research and Treatment Clinic at CAMH. He is Professor at University of Toronto in the departments of Family and Community Medicine, Pharmacology and Toxicology, Psychiatry ,Institute of Medical Sciences and Dalla Lana School of Public Health.

• PART I Introduction to anandamide1 Regulation of the levels of anandamide and its bioactive congeners by biosynthesis and degradationVincenzo Di Marzo and Cristoforo Silvestri2 Imaging the endocannabinoid enzyme fatty acid amide hydrolase in the living human brainClaire Shyu, Shamantha Lora, Laura M. Best, Sheldon Bereznick and Isabelle Boileau3 Anandamide: From modulation of neuronal excitation to antimicrobial activities--What is in common?Ronit Vogt Sionov and Doron SteinbergPART II Anandamide in diseases4 Anandamide and mood disordersJacklynn M. Fitzgerald and Cecilia J. Hillard5 Anandamide and anxietySara Liane Kroll and Leah M. Mayo6 Anandamide and disease. Role in stress, fear, and PTSDLuke J. Ney and Allison Matthews7 Anandamide in disease: Role in psychosisM. Belen Blasco, Carlos A. Pretell Annan and Romina Mizrahi8 Anandamide in personality disordersNathan J. Kolla and Michelle De Pol9 A brief review of anandamide in cannabis use and cannabis use disorderRaesham Mahmood, Claudia Poluga, Isabelle Boileau and Laura M. Best10 Anandamide signaling dysfunction in the development of alcohol use disordersBalapal S. Basavarajappa11 Role of Anandamide in Nicotine AddictionBernard Le Foll12 The role of anandamide in the sleep--wake cycleMonica Mendez Dıaz, Yalitza Azucena Alvarado Ramırez, Aline Ostos Valverde, Oscar E. Prospero Garcıa and Andrea M. Herrera Solıs13 Anandamide in disease: The good and bad in epilepsyRenaud Gom, Pasindu Wickramarachchi, Roberto Colangeli and G. Campbell Teskey14 Role of anandamide in Alzheimer’s diseaseDina Medina-Vera and Simone Tambaro15 The role of anandamide in digestive and defensive functions of the gutKeith A. Sharkey and Derek K.L. Tsang16 The role of anandamide and the endocannabinoids in the treatment and regulation of nausea and vomitingErin M. Rock and Linda A. Parker

Dr. Bernard Le Foll is a Clinician Scientist specializing in Addiction. He is Chair of Addiction Psychiatry within the Department of Psychiatry of University of Toronto. He is Head of the Translational Addiction Research Laboratory in the Campbell Family Mental Health Research Institute. He is also the Lead, Clinical Research Innovation Service within the Addiction Division at CAMH. He is Head of the Alcohol Research and Treatment Clinic at CAMH. He is Professor at University of Toronto in the departments of Family and Community Medicine, Pharmacology and Toxicology, Psychiatry ,Institute of Medical Sciences and Dalla Lana School of Public Health.

• PART I Introduction to anandamide1 Regulation of the levels of anandamide and its bioactive congeners by biosynthesis and degradationVincenzo Di Marzo and Cristoforo Silvestri2 Imaging the endocannabinoid enzyme fatty acid amide hydrolase in the living human brainClaire Shyu, Shamantha Lora, Laura M. Best, Sheldon Bereznick and Isabelle Boileau3 Anandamide: From modulation of neuronal excitation to antimicrobial activities--What is in common?Ronit Vogt Sionov and Doron SteinbergPART II Anandamide in diseases4 Anandamide and mood disordersJacklynn M. Fitzgerald and Cecilia J. Hillard5 Anandamide and anxietySara Liane Kroll and Leah M. Mayo6 Anandamide and disease. Role in stress, fear, and PTSDLuke J. Ney and Allison Matthews7 Anandamide in disease: Role in psychosisM. Belen Blasco, Carlos A. Pretell Annan and Romina Mizrahi8 Anandamide in personality disordersNathan J. Kolla and Michelle De Pol9 A brief review of anandamide in cannabis use and cannabis use disorderRaesham Mahmood, Claudia Poluga, Isabelle Boileau and Laura M. Best10 Anandamide signaling dysfunction in the development of alcohol use disordersBalapal S. Basavarajappa11 Role of Anandamide in Nicotine AddictionBernard Le Foll12 The role of anandamide in the sleep--wake cycleMonica Mendez Dıaz, Yalitza Azucena Alvarado Ramırez, Aline Ostos Valverde, Oscar E. Prospero Garcıa and Andrea M. Herrera Solıs13 Anandamide in disease: The good and bad in epilepsyRenaud Gom, Pasindu Wickramarachchi, Roberto Colangeli and G. Campbell Teskey14 Role of anandamide in Alzheimer’s diseaseDina Medina-Vera and Simone Tambaro15 The role of anandamide in digestive and defensive functions of the gutKeith A. Sharkey and Derek K.L. Tsang16 The role of anandamide and the endocannabinoids in the treatment and regulation of nausea and vomitingErin M. Rock and Linda A. Parker