bokomslag Alternative Splicing and Disease
Kropp & själ

Alternative Splicing and Disease

Philippe Jeanteur

Pocket

4359:-

Funktionen begränsas av dina webbläsarinställningar (t.ex. privat läge).

Uppskattad leveranstid 3-7 arbetsdagar

Fri frakt för medlemmar vid köp för minst 249:-

Andra format:

  • 257 sidor
  • 2010
Splicing of primary RNA transcript, i.e. removal of introns and joining of exons to produce mature mRNAs competent for translation into proteins, is a quasi-systematic step of gene expression in higher organisms. However, this process is not unequivocal but can follow alternate pathways. Alternative splicing of a given transcript can therefore yield several distinct mRNAs encoding as many different proteins. Its full biological significance has not been appreciated until it was recognized that alternative splicing is so general as to affect about 75% of all human genes. Therefore, alternative splicing not only vastly increases protein diversity but also offers numerous opportunities for aberrant splicing events with pathological consequences.
  • Författare: Philippe Jeanteur
  • Format: Pocket/Paperback
  • ISBN: 9783642070815
  • Språk: Engelska
  • Antal sidor: 257
  • Utgivningsdatum: 2010-11-30
  • Förlag: Springer-Verlag Berlin and Heidelberg GmbH & Co. K