Alpha 1 - Antitrypsin Deficiency

Biology-Pathogenesis-Clinical Manifestations-Therapy

Inbunden, Engelska, 1995

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Providing a broad overview of basic and clinical aspects of alpha 1-antitrypsin (a 1AT) deficiency, this up-to-date reference discusses the complex pathobiological processes underlying the pathogenesis of a1AT deficiency, describes the a1AT gene and its promoter, and details specific therapies to prevent the major clinical manifestations of the disorder.

Produktinformation

Utgivningsdatum1995-10-26
Mått152 x 229 x 27 mm
Vikt816 g
FormatInbunden
SpråkEngelska
SerieLung Biology in Health and Disease
Antal sidor478
FörlagTaylor & Francis Inc
ISBN9780824788483

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IntroductionAlpha 1-Antitrypsin Deficiency: An Introduction, Andrea Mastrangeli and Ronald G. CrystalBiology and PathobiologyAlpha 1-Antitrypsin Gene and Promoter, John G. Hay, Motoyoshi Suzuki, and Ronald G. CrystalAlpha 1-Antitrypsin Gene Evolution, Toshihiro Nukiwa, Fumitaka Ogushi, and Ronald G. CrystalAlpha 1-Antitrypsin Genotypes and Phenotypes, Mark BrantlyStructure and Expression of the Human Neutrophil Elastase Gene, Kunihiko YoshimuraThe Three-Dimensional Structure of a1AT, Richard A. Engh and Wolfman BodeThe Three-Dimensional Structure of Human Neutrophil Elastase, Wolfram BodeKinetics of Neutrophil Elastase Inhibition In Vivo, Joseph G. BiethAlpha 1-Antitrypsin Gene Expression in Neutrophils and Other Cells, Roland M. du BoisAlpha 1-Antitrypsin Gene Expression in Hepatocytes, Alfredo Nicosia and Paola MonaciAlpha 1-Antitrypsin Gene Expression in Mononuclear Phagocytes, Gregg Joslin and David H. PerlmutterTransgenic Animals with the a1AT Promoter, Wilfried Dalemans, Frédéric Perraud, Dalila Ali-Hadji, Sophie Jallat, and Andrea PaviraniChemistry and Biology of Secretory Leukoprotease Inhibitor, David F. Carmichael and Kjell OhlssonClinical ManifestationsLaboratory Diagnosis of a1AT Deficiency, Mark BrantlyClinical Manifestations of a1AT Deficiency, Noel G. McElvaney and Ronald G. CrystalLung Function and a1AT Deficiency, Alan F. Barker, Ray G. D'silva, and A. Sonia BuistReactive Airways Disease and a1AT Deficiency, Robert J. FallatNatural History of a1AT Deficiency, Janet Wittes and Margaret C. WuThe Prevalence of a1AT Deficiency Outside the United States and Europe, Toshihiro Nukiwa, Kuniaki Seyama, and Shiro KiraThe National Institutes of Health National Heart, Lung and Blood Institute Registry for Patients with Severe Deficiency of Alpha 1-Antitrypsin, James K. StollerTreatmentTherapy of a1AT Deficiency, Noel G. McElvaney and Robert G. CrystalAugmentation of Liver Production, Mark D. WewersLow-Molecular-Weight Inhibitors of Neutrophil Elastase, James C. Powers, R. Richard Plaskon, and Chih-Min Kama1AT Deficiency and Liver Transplantation, David H. Van Thiel and Thomas E. StarzlLung Transplantation for a1AT Deficiency Emphysema, Elbert P. Trulock and Joel D. Cooper