The editors and contributors include most of the key researchers working on these topics worldwide.

• Tribute.- Grzegorz Rozenberg: A Magical Scientist and Brother.- Sequence Discovery, Generation, and Analysis.- Monotony and Surprise.- Information Content of Sets of Biological Sequences Revisited.- Duplication in DNA Sequences.- Sequence and Structural Analyses for Functional Non-coding RNAs.- Gene Assembly in Ciliates.- Strategies for RNA-Guided DNA Recombination.- Reality-and-Desire in Ciliates.- Template-Guided Recombination: From Theory to Laboratory.- Nanoconstructions and Self-assembly.- DNA Cages with Icosahedral Symmetry in Bionanotechnology.- Applying Symmetric Enumeration Method to One-Dimensional Assembly of Rotatable Tiles.- A Self-assembly Model of Time-Dependent Glue Strength.- The Perils of Polynucleotides Revisited.- Algorithmic Control: The Assembly and Operation of DNA Nanostructures and Molecular Machinery.- Membrane Computing.- On Nonuniversal Symport/Antiport P Systems.- Spiking Neural P Systems. Recent Results, Research Topics.- Membrane Computing Schema: A New Approach to Computation Using String Insertions.- Formal Models and Analysis.- Finite Splicing: Generative Capacity, New Models and Complexity Aspects.- Formal Models of the.- Understanding Network Behavior by Structured Representations of Transition Invariants.- Quantitative Verification Techniques for Biological Processes.- A New Mathematical Model for the Heat Shock Response.- Process Calculi and Automata.- Artificial Biochemistry.- Process Calculi Abstractions for Biology.- Deriving Differential Equations from Process Algebra Models in Reagent-Centric Style.- Programmable DNA-Based Finite Automata.- Biochemical Reactions.- A Multi-volume Approach to Stochastic Modeling with Membrane Systems.- Programmability of Chemical Reaction Networks.- Log-gain Principles forMetabolic P Systems.- Hybrid Method for Simulating Small-Number Molecular Systems.- Broader Perspective.- On Involutions Arising from Graphs.- Parallel Computing by Xeroxing on Transparencies.- Some Undecidable Dynamical Properties for One-Dimensional Reversible Cellular Automata.- On Using Divide and Conquer in Modeling Natural Systems.- No Molecule Is an Island: Molecular Evolution and the Study of Sequence Space.- Niching Methods: Speciation Theory Applied for Multi-modal Function Optimization.- On the Concept of -regulatory Information: From Sequence Motifs to Logic Functions.

"In a real sense, this book answers the question, 'What is the cutting edge of research connecting computer science with the biological sciences?' ... [I]ts breadth of content is impressive, and its combination of advanced tutorials with ambitious new proposals is scientifically exciting. ... [The book] will best serve TCS researchers who are looking for new questions to ask, and for new areas in which to apply their skills." (Aaron Sterling, The Book Review Column 43-3, 2012)