Alcohol, Cell Membranes, and Signal Transduction in Brain

Häftad, Engelska, 2012

AvChrister Alling,Ivan Diamond,Steven W. Leslie,Grace Y. Sun,W. Gibson Wood

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The second section comprises chapters on NMDA and 5-HT3 receptors, including new aspects on alcohol neurotoxicity and the molecular heterogeneity that may underlie differences in alcohol sensitivity as well as chapters on GABA-gated chloride flux, and calcium channels.

Produktinformation

Utgivningsdatum2012-10-23
Mått178 x 254 x 19 mm
Vikt641 g
FormatHäftad
SpråkEngelska
Antal sidor320
Upplaga1993
FörlagSpringer-Verlag New York Inc.
ISBN9781461360520

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I. Lipid Structure, Domains and Proteins.- Molecular Mechanisms of Ethanol and Anesthetic Actions: Lipid- and Protein-Based Theories.- Membrane Cholesterol and Ethanol: Domains, Kinetics, and Protein Function.- The Effects of Ethanol on Polyunsaturated Fatty Acid Composition.- Relevant Effects of Dietary Polyunsaturated Fatty Acids on Synaptic Membrane Responses to Ethanol and Chronic Alcohol Intoxication.- Chronic Ethanol Treatment Increases the Incorporation of [14C]-Serine into Phosphatidylserine in Neuroblastoma x Glioma Cells.- Ethanol-Induced Changes in Signal Transduction via Formation of Phosphatidylethanol.- Phosphatidylethanol Effects on Inositol 1,4,5-Trisphosphate Levels and Protein Kinase C Activity in NG108-15 Cells.- Multiple Actions of Ethanol on Acetylcholine Receptors.- II. Receptors and Ion Channels.- Sensitivity of NMDA Receptors to Acute and in Utero Ethanol Exposure.- Neurotransmitter-Gated Ion Channels as Molecular Sites of Alcohol Action.- Molecular Mechanisms of Alcohol Neurotoxicity.- Molecular Properties of an NMD A Receptor Complex and Effects of Ethanol on the Expression of this Complex.- In Vivo Studies of Ethanol Interactions with N-Methyl-D-Asparatate Systems in Rat Brain.- Actions of Alcohols and Other Sedative/Hypnotic Compounds on Cation Channels Associated with Glutamate and 5-HT3 Receptors.- Mechanisms That Mediate Ethanol-Induced Increases in Dihydropyridine-Sensitive Calcium Channels.- Alcohol: Effects on GABAA Receptor Function and Gene Expression.- Control of Alcoholism by Treatment with SKV, a Herbal Drug Mixture from India.- III. Second Messenger Systems and Kinases.- Nucleoside Transport and Ethanol-Induced Heterologous Desensitization.- Effects of Acute and Chronic Ethanol Administration on the Poly-Phosphoinositide SignalingActivity in Brain.- Ethanol and Phospholipid Dependent Signal Transduction: The View from the Liver.- Phospholipase C coupled G-Proteins: Molecular Targets of Ethanol.- Selective Effects of Ethanol on Neuropeptide-Mediated Polyphosphoinositide Hydrolysis and Calcium Mobilization.- The Muscarinic Receptor-Stimulated Phosphoinositide Metabolism as a Potential Target for the Neurotoxicity of Ethanol during Brain Development.- Effects of Ethanol on Receptor-Mediated Phospholipase D Activity in Human Neuroblastoma Cells.- Ethanol and Cell Tyrosine Kinase.- IV. Gene Expression.- Regulation of Neuronal Gene Transcription by Ethanol.- Super-Induction of c-fos-like Protein in Bovine Adrenal Chromaffin Cells Associated with Ethanol Withdrawal.- Effect of Acute and Chronic Administration of Ethanol on c-fos Expression in Brain.