Agrobacterium: From Biology to Biotechnology

Häftad, Engelska, 2010

AvTzvi Tzfira,Vitaly Citovsky

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Agrobacterium is a plant pathogen which causes the “crown-gall” disease, a neoplastic growth that results from the transfer of a well-defined DNA segment (“transferred DNA”, or “T-DNA”) from the bacterial Ti (tumor-inducing) plasmid to the host cell, its integration into the host genome, and the expression of oncogenes contained on the T-DNA. The molecular machinery, needed for T-DNA generation and transport into the host cell and encoded by a series of chromosomal (chv) and Ti-plasmid virulence (vir) genes, has been the subject of numerous studies over the past several decades. Today, Agrobacterium is the tool of choice for plant genetic engineering with an ever expanding host range that includes many commercially important crops, flowers, and tree species. Furthermore, its recent application for the genetic transformation of non-plant species, from yeast to cultivated mushrooms and even to human cells, promises this bacterium a unique place in the future of biotechnological applications. The book is a comprehensive volume describing Agrobacterium's biology, interactions with host species, and uses for genetic engineering.

Produktinformation

Utgivningsdatum2010-10-29
Mått155 x 235 x 46 mm
Vikt1 124 g
FormatHäftad
SpråkEngelska
Antal sidor750
FörlagSpringer-Verlag New York Inc.
ISBN9781441924735

Tillhör följande kategorier

Biokemisk teknik inom Naturvetenskap och teknik
Botanik inom Naturvetenskap och teknik
Växtböcker inom Djur och Natur
Biologi inom Naturvetenskap och teknik

Agrobacterium: A disease-causing bacterium.- A Brief History of Research on Agrobacterium Tumefaciens: 1900–1980s.- Agrobacterium and Plant Biotechnology.- The Agrobacterium Tumefaciens C58 Genome.- Agrobacterium—Taxonomy of Plant-Pathogenic Rhizobium Species.- The Initial Steps in Agrobacterium Tumefaciens Pathogenesis: Chemical Biology of Host Recognition.- Agrobacterium-Host Attachment and Biofilm Formation.- Production of a Mobile T-DNA by Agrobacterium Tumefaciens.- Translocation of Oncogenic T-DNA and Effector Proteins to Plant Cells.- Intracellular Transport of Agrobacterium T-DNA.- Mechanisms of T-DNA integration.- Agrobacterium Tumefaciens-Mediated Transformation: Patterns of T-Dna Integration Into the Host Genome.- Function of Host Proteins in The Agrobacterium-Mediated Plant Transformation Process.- The Oncogenes of Agrobacterium Tumefaciens and Agrobacterium Rhizogenes.- Biology of Crown Gall Tumors.- The Cell-Cell Communication System of Agrobacterium Tumefaciens.- Horizontal Gene Transfer.- Agrobacterium-Mediated Transformation of Non-Plant Organisms.- The Bioethics and Biosafety of Gene Transfer.- Agrobacterium-Mediated Gene Transfer: A Lawyer’s Perspective.

From the reviews: "A compilation of many aspects of Agrobacterium research, with each chapter authored by experts in the field. Though the book is heavily oriented toward the genetic/molecular basis of the gene transfer process, it includes the history of Agrobacterium research, nomenclature, and basic biology of the bacterial/plant interaction. The final chapters review bioethics and legal aspects of Agrobacterium-mediated gene transfer. Summing Up: Recommended. Graduate students and researchers/faculty." (L. M. Baird, CHOICE, Vol. 45 (11), August, 2008)

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