Aging Research in Yeast

Inbunden, Engelska, 2011

Av Michael Breitenbach, S. Michal Jazwinski, Peter Laun, Michal S. Jazwinski

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Replicative aging, in which only the mother cell ages while the daughter cell resets the clock to zero is a model for the aging of stem cell populations in humans, while chronological aging (measured by survival in stationary phase) is a model for the aging processes in postmitotic cells (for instance, neurons of the brain).

Produktinformation

Utgivningsdatum2011-11-19
Mått155 x 235 x 25 mm
Vikt735 g
FormatInbunden
SpråkEngelska
SerieSubcellular Biochemistry
Antal sidor368
Upplaga2012
FörlagSpringer
ISBN9789400725607

Tillhör följande kategorier

Geriatrik inom Medicin
Biologi inom Naturvetenskap och teknik
Biovetenskap inom Naturvetenskap och teknik
Cellbiologi inom Naturvetenskap och teknik

1. Preface and Introduction to Aging research in Yeast.- 2.Oxidative stresses and ageing.- 3.The role of Mitochondria in the aging processes of yeast.- 4.The Retrograde Response and Other Pathways of Interorganelle Communication in Yeast Replicative Aging.- 5. Chronological Aging in Saccharomyces cerevisiae.- 6. Still waters run deep: Aging and the survival of quiescent and non-quiescent cells in yeast stationary-phase cultures.- 7. Maximising the yeast chronological lifespan.- 8.Amino Acid Homeostasis and Chronological Longevity in Saccharomyces cerevisiae.- 9. DNA damage and DNA replication stress in yeast models of aging.- 10.Yeast aging and apoptosis.-11. Cellular homeostasis in fungi: Impact on the aging process.- 12.Genome-wide analysis of yeast aging.- 13. Genetic Approaches to Aging in Budding and Fission Yeasts: New Connections and New Opportunities.- 14. Evolution of asymmetric damage segregation: a modelling approach.-15. Cellular ageing and the actin cytoskeleton.

From the reviews: "This book compiles some of the most exciting and promising research to date in the fields of anti-aging, longevity, and possibly even rejuvenation. The authors' research examines the role of senescence in yeast and how it may relate to the chaotic autophagy of cancer cells. In sum, Aging Research will stir interest in both scientific and non-scientific arenas." (The Electric Review, October, 2012)