This book is a multi-author treatise on the most outstanding research problems in the field of the aeronomy of the Earth’s atmosphere and ionosphere, encompassing the science covered by Division II of the International Association of Geomagnetism and Aeronomy (IAGA). It contains several review articles and detailed papers by leading scientists in the field. The book is organized in five parts: 1) Mesosphere-Lower Thermosphere Dynamics and Chemistry; 2) Vertical Coupling by Upward Propagating Waves; 3) Ionospheric Electrodynamics and Structuring; 4) Thermosphere- Ionosphere Coupling, Dynamics and Trends and 5) Ionosphere-Thermosphere Disturbances and Modeling. The book consolidates the progress achieved in the field in recent years and it serves as a useful reference for graduate students as well as experienced researchers.