In this issue of Pediatric Clinics of North America, guest editors Drs. Jonathan R. Dillman, Brian Coley, and Andrew T. Trout bring their considerable expertise to the topic of Advances in Pediatric Imaging. Top experts cover core topics such as radiation risk, contrast media safety, and imaging modality fundamentals with an emphasis on imaging appropriateness and clinical relevance. They also discuss cutting-edge innovations including artificial intelligence, rapid MRI protocols, nuclear medicine, point-of-care ultrasound, and future directions.