This book constitutes the refereed proceedings of the 22nd International Conference on Advances in Mobile Computing and Multimedia Intelligence, MoMM 2024, held in Bratislava, Slovak Republic, during December 2–4, 2024. The 10 full papers and 8 short papers in this book were carefully reviewed and selected from 34 submissions. They were organized in topical sections as follows: wearable and sensor-based data for human performance and interaction; mobile user experience, motivation, and behavior; medical and cognitive health applications; image, video, and multimedia processing; software and system intelligence.