Advances in Hemophilia Treatment

From Genetics to Joint Health

Häftad, Engelska, 2023

Av E. Carlos Rodríguez-Merchán, E. Carlos Rodriguez-Merchan

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This book offers a comprehensive and state of the art overview of hemophilia management by reviewing all most recent advances and cutting edge information in this fast evolving field. As hemophilia patients are often affected by joint problems it also provides clear guidance on the surgical treatment of musculo-skeletal manifestations.The first part is devoted to the disease’s pathophysiology (differentiating hemophilia A and B), genetics, pharmacotherapy – including replacement and non-replacement therapy – and gene therapy, as well as quality of life issues – also related to hemophilia carriers. The second part is then focused on joint problems, ranging from joint health assessment and pain control to surgical treatment of acute hemarthrosis and hemophilic arthropathy, i.e. radiosynovectomy, total joint arthroplasty and arthroscopic joint debridement.Written by experts drawn from leading institutions involved in treatment of hemophilia andrelated joint problems, this book offers a valuable resource to hematologists, orthopedic surgeons, rehabilitation physicians, radiologists, and pharmacy researchers.

Produktinformation

Utgivningsdatum2023-04-23
Mått178 x 254 x 10 mm
Vikt400 g
FormatHäftad
SpråkEngelska
Antal sidor173
FörlagSpringer Nature Switzerland AG
ISBN9783030939922

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E. Carlos Rodríguez-Merchán is a Specialist in Orthopedic Surgery and “Emeritus” Consultant Orthopedic Surgeon currently working at the Department of Orthopedic Surgery, La Paz University Hospital, Madrid, Spain. Dr. Rodríguez-Merchán graduated from Complutense University with a degree in Medicine and Surgery in 1974, and subsequently completed a PhD in Medicine and Surgery. He is a former Associate Professor of Orthopedics at the Autonomous University of Madrid. Dr. Rodríguez-Merchán is the author of more than 300 articles in peer-reviewed PubMed-cited journals, as well as 11 books.

1. Pathophysiology of hemophilia.- 2. Genetics of Hemophilia A and B.- 3. Inhibitors in Hemophilia A.- 4. Immune Tolerance In Patients with Hemophilia A.- 5. Hemophilia A: New drugs.- 6. Inhibitors in Hemophilia B.- 7. Immune Tolerance Induction in Hemophilia B.- 8. Hemophilia B: New Drugs.- 9. Management of Hemophilia Carriers.- 10. Pharmacoeconomic Aspects in Hemophilia.- 11. Assessment of Joint Health and Outcome Measures in Hemophilia.- 12. Musculoskeletal Medicine in Hemophilia.- 13. Management of Acute Hemarthrosis in Hemophilia (Including Joint Aspiration).- 14. Hemophilic Arthropathy: Radiosynovectomy.- 15. Hemophilic Arthropathy: Arthroscopic Joint Debridement.- 16. Hemophilic Arthropathy: Total Joint Arthroplasty.- 17. Hemophilic Arthropathy: Other Orthopedic Procedures.- 18. Gene Therapy in Hemophilia: Latest Advances.- 19.A Summary of the Recent Recommendations of the WFH.