Advances in Genomics and Neurosciences for Neurologic and Behavioral Disorders

Häftad, Engelska, 2026

2 449 kr

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Advances in Genomics and Neurosciences for Neurologic and Behavioral Disorders explores the latest breakthroughs in genomics and neurosciences, providing essential insights for understanding, diagnosing, and managing neurodevelopmental, psychiatric, and neurodegenerative disorders. The book highlights the intersection of genetic and genomic diagnostic techniques with brain function and structure analysis to enhance therapeutic strategies. Sections cover a wide range of topics, including the analysis of brain circuits, synapses, and neural activity, as well as the role of ion channels and neurotrophins in brain function. It examines advanced genetic and genomic diagnostic methods such as chromosome studies, gene sequencing, RNA analysis, and metabolite profiling.

The book also addresses neurodevelopmental disorders like cerebral palsy, epilepsy, and autism, psychiatric disorders such as schizophrenia and thought disorders, and the molecular biology of memory and age-related cognitive decline. Organized into five sections, the book includes chapters on the latest techniques for brain analysis, genetic diagnostics, neurodevelopmental and psychiatric disorders, aging-related impairments, and new therapeutic approaches. Key topics include brain regions and circuits, new methods for studying these areas, and the relevance of this information for accurate diagnosis and patient care.

Explores advances in genomics and neurosciences relevant to neurodevelopmental, psychiatric, and neurodegenerative disorders
Discusses cutting-edge genetic and genomic diagnostic techniques for accurate diagnosis and personalized treatment
Analyzes brain circuits, synapses, and dendrites to enhance understanding of brain-related disorders and diagnostic methods
Reviews therapeutic targets and pharmacological advances, including gene and RNA-directed therapies and optogenetic therapies
Provides real-world applications and case studies to bridge the gap between research and patient care

Produktinformation

Utgivningsdatum2026-10-01
Mått191 x 235 x undefined mm
Vikt450 g
FormatHäftad
SpråkEngelska
Antal sidor425
FörlagElsevier Science
ISBN9780443451836

Tillhör följande kategorier

Farmakologi inom Medicin
Biovetenskap inom Naturvetenskap och teknik

Dr. Moyra Smith is a Professor Emerita in the Department of Pediatrics and Human Genetics, College of Health Sciences, at the University of California, Irvine, and in past years has held appointments at the National Institutes of Health and Johns Hopkins University. In 2017, the UCI Emeriti Association awarded Dr. Smith the UCI Outstanding Emerita Award in recognition of her continuing research on genetics and genomics, strong record of publications, active engagement with programs in the Department of Pediatrics, mentoring of graduate students, and involvement with the CART Autism Center at UCI. Dr. Moyra Smith has published more than 100 scientific articles in peer-reviewed journals such as Frontiers in Molecular Biosciences, Molecular Psychiatry, the Journal of Medical Genetics (JMG), and Cytogenetics Cell Genetics.

Section 1: Advances in Analyses of Structures and Functions in Brain1. Electrophysiology and key discoveries2. Ion channels and brain activity3. Cortical Circuits structures and analyses4. NeurotrophinsSection 2: Genetic and Genomic Diagnostic Techniques5. Chromosome studies and microarrays6. Gene sequencing exome sequencing genomic sequencing7. RNA and transcription analyses 8. Metabolite analysesSection 3: Neurodevelopmental Disorders9. Neurodevelopmental defects10. Cerebral Palsy and Movement disorders11. Epilepsy12. Developmental delay13. Behavioral disorders including autism and attention deficit hyperactivity disordersSection 4: Psychiatric Disorders14. Transdiagnostic dimensions, maladaptive behaviors, distress15. Thought disorders16. Cross-disorder psychiatry17. Schizophrenia18. Genetics and Genomics in PsychiatrySection 5: Impaired Function in Aging19. Molecular biology of memory20. Age related memory decline hippocampus and synaptic impairment and high risk genes21. Mitochondrial functional impairment in aging22. Alzheimer disease and risk loci23. Epigenetic and transcription changes in aging24. Dementia and neuropathology25. Gene defects leading to abnormal protein aggregates26. Fronto-temporal dementia27. Vascular dementia28. Parkinsonism and related gene defects29. Amyotrophic lateral sclerosis30. Vascular dementia31. Macular degenerations and advances in therapy