Advances in Enzymology and Related Areas of Molecular Biology, Volume 75

ERIC J. TOONE is Professor of Chemistry and Professor of Biochemistry at Duke University in Durham, North Carolina.

• Contributors. Preface.Abstracts.Molecular Paleoscience: Systems Biology from the Past (Steven A. Benner, Slim O. Sassi, and Eric A. Gaucher).A Structure-Centric View of Protein Evolution, Design, and Adaptation (Eric J. Deeds and Eugene I. Shakhnovich).Mechanisms of Protein Evolution and Their Application to Protein Engineering (Margaret E. Glasner, John A. Gerlt, and Patricia C. Babbitt).Novel Enzymes Through Design and Evolution (Kenneth J. Woycechowsky, Katherina Vamvaca, and Donald Hilvert).Author Index.Subject Index.