Advances in Blood Flow Quantification Methods for Diagnosis, Monitoring, Prediction, and Personalized Treatment of Cardiovascular Disease

Dr. Zahra K. Motamed PhD, MSc, directs the Cardiovascular Research Group and is an Associate Professor in the Department of Mechanical Engineering at McMaster University. She is a member of the Professional Engineers of Ontario, with over 17 years of experience in cardiovascular diseases and their devices. She served as the Chair of the 2021 NSERC Research Tool and Instruments Selection Committee for Mechanical Engineering. She is on the editorial board of Scientific Reports, and for the Journal of Frontiers in Bioengineering and Biotechnology. She was a handling Editor in Frontiers in Cardiovascular Medicine. She is currently the invited lead guest editor of Frontiers in Bioengineering and Biotechnology, and an invited guest editor of Scientific Reports (a Nature journal). Her research interests are mainly in the areas of computational fluid dynamics for the study of cardiovascular disease, translational and basic cardiovascular mechanics, and developing quantitative diagnostic, predictive, and intervention-optimization tools.Jose M. de La Torre Hernández MD, PhD, FESC is an interventional cardiologist and head of the Hemodynamics and Interventional Department of the Marques de Valdecilla University of Santander. He is the president of the Spanish Society of Cardiology, and is a fellow of the European Society of Cardiology. Dr. Hernández is the former associate director of the Trans Catheter Therapeutics and TCT conferences (USA). Dr. Hernández has participated in over 75 clinical trials for cardiac devices and has been an author in more than 220 peer-reviewed papers and 7 book chapters. Dr. Hernández currently serves as the Founder and Editor in Chief of REC: Interventional Cardiology, editorial consultant in JACC Interventions and section editor in Eurointervention. Dr. Hernández brings a vast clinical insight essential to the success of this book, specifically in terms of future clinical device adoptability.Philippe Pibarot, DVM, PhD, FACC, FAHA, FASE, FESC, FCCS is a professor in the Department of Medicine at Laval University, holds the Canada Research Chair in Valvular Heart Disease, and is head of Cardiology Research at Québec Heart & Lung Institute (IUCPQ). He is principal investigator in studies and trials funded by a grant from the Canadian Institutes of Health Research, and directs the Echocardiography Core Laboratory at IUCPQ.He is associate editor for the Structural Heart and Eurointervention journals, Imaging section editor for the Journal of the American College of Cardiology, and Editor-in-Chief of the Journal of the Heart Valve Society. He received the Annual Achievement Award of the Canadian Society of Echocardiography, the Canadian Cardiovascular Society Research Achievement Award, the Feigenbaum Lecture Award, and the CIHR-ICRH/CCS Distinguished Lecturer Award in Cardiovascular Sciences. His research program develops and validates patient-oriented approaches to improve diagnosis, prevention, and treatment of VHD.

• IntroductionHemodynamics: Fundamentals and roles in atrial fibrillationAdvances in blood flow quantification methods for diagnosis and monitoring of cardiovascular diseaseAdvances in blood flow quantification methods for prediction of cardiovascular interventionsComputational predictive modeling of valve performance and risks toward personalization of TAVR with lifetime managementAdvances in 4D flow MRI blood flow quantification methods for prediction of cardiovascular interventionAdvancing clinical interventions through patient‑specific in‑vitro simulators: Challenges, techniques and future directionsEnhancing patient management with TAVR and coronary disease through computational modelingImpact of flow in assessment and prognosis of valvular heart diseasesTranslational machine learning in cardiac disease: Advancing diagnosis, monitoring, and predictionBridging the critical gap in cardiovascular biomechanics: From computational models to clinical applications