This book constitutes the refereed proceedings of the 38th International Conference on Industrial, Engineering and Other Applications of Applied Intelligent Systems on Advances and Trends in Artificial Intelligence, IEA/AIE 2025, held in Kitakyushu, Japan, in July 1–4, 2025.The 80 full papers and 9 short papers included in this book were carefully reviewed and selected from 130 submissions. They focus on the following topical sections:Part I: Reinforcement Learning; Optimization; Natural Language Processing; Multi-Agent; Machine Learning and Decision Making; Knowledge Representation; Data Engineering; Large Language Model; Computer Vision.Part II: Robotics; Education; Cyber Security; Healthcare and Medical Applications; Advanced Applied Intelligence Methodologies and Applications; Intelligent Systems and e-Applications; Industrial and Engineering Applications.